A novel likely pathogenic SNCA variant associated with Parkinson’s disease
Objective: To report a novel SNCA likely pathogenic variant. Background: The A53T mutation in the SNCA gene, encoding alpha-synuclein (a-syn), was the first established genetic…GCH1 variants contribute to risk and earlier age at onset in Parkinson’s disease
Objective: Our aim was to identify the potential role of known genetic components of GCH1, including rare and common variants in coding and non-coding regions,…Diagnostic value of vagus nerve ultrasound in Parkinson’s disease
Objective: To detect by the ultrasound (US) the possible presence of vagus nerve atrophy in patients with PD and its relation to severity of motor,…Noradrenergic terminal and locus coeruleus cell loss may be uncoupled in Parkinson’s disease – a PET and MRI multi-modal imaging study
Objective: To assess multimodal imaging of the noradrenergic system: magnetic resonance imaging (MRI) neuromelanin contrast of the locus coeruleus (LC) and noradrenalin transporter density with…Alterations in functional networks contribute to depression in Parkinson’s disease: A resting-state functional magnetic resonance imaging study
Objective: The aim of this research was to investigate alterations in functional brain networks in PD patients with depression (DPD) and their association with demographic…Loss of cortical inhibition in Parkinson’s disease
Objective: To evaluate motor cortex inhibition at different stages of Parkinson’s disease (PD). Background: In PD, striatal dopamine depletion produces profound alterations in the neural…Pain syndrome in Parkinson’s disease: neurophysiological and MRI morphometric features
Objective: Investigation of the neurophysiological disorders and identify their structural correlates in the brain by MRI studies with using voxel-based morphometry to reveal subtle changes…Does constipation predict cognitive impairment and dementia in de novo Parkinson’s disease patients? A multi-cohort longitudinal data analysis
Objective: To investigate if constipation predicts the development of cognitive impairment (CI) and dementia in de novo Parkinson’s disease (PD). Background: Constipation is one of…Effects of Sleep Disorders on the Quality of Life in Parkinson’s Disease: A Study of 84 Ibadan Patients
Objective: To assess the effects of sleep disorders on the quality of life in PD patients. Background: Parkinson’s disease is a progressive neurodegenerative disease. The…Urinary Symptoms and Parkinson’s Disease: The Patient’s Perspective
Objective: To learn about prevalence rates and the impact of urinary symptoms on day-to-day function and quality of life from the patient’s perspective. Background: Urinary…
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