Exploring feasibility and efficacy of a ballet-based intervention in advanced Parkinson’s disease.
Objective: To explore feasibility and acute and longitudinal effects of the PD-Ballet intervention in advanced Parkinson’s disease(PD)(Hoehn&Yahr [HY] stages IV-V). Background: Programmed physical activity such…Hand and Arm Function in Persons with De Novo Parkinson’s Disease
Objective: To evaluate hand and arm function and its association with motor symptoms as well as activities of daily living (ADL) in de novo Parkinson's…Evaluating Fall Risk in People with Parkinson’s Disease Using a Novel Comprehensive Posturography Assessment
Objective: To determine if a comprehensive balance assessment on a posturography system can identify retrospective Fallers from Non-fallers in people with Parkinson’s disease (PwPD). We…Gender Disparities in Quality of Life Domains Among Hispanic Individuals with Parkinson’s Disease: A Comparative Analysis
Objective: This study aims to determine gender differences in the quality of life of Parkinson's disease (PD) among Hispanic individuals. Background: PD profoundly affects various…Gathering Prodromal Participant Perspective on Receiving Personal Research Information
Objective: To understand perceptions and expectations of people with prodromal Parkinson’s disease (PD) around receiving personal research information. Background: There is limited information on the…Long-Term Efficacy of 24-hour Subcutaneous Levodopa/Carbidopa Infusion (ND0612) for Motor Fluctuations in Parkinson’s Disease
Objective: Describe 1-year efficacy outcomes from the ongoing open-label extension (OLE) phase of the BouNDless study (NCT04006210) of subcutaneous levodopa/carbidopa infusion (ND0612) for fluctuating PD…The relationship between pain threshold and striatal dopamine function in Parkinson’s Disease
Objective: This study aims to determine the relationship between pain threshold and striatal dopamine function in people with Parkinson's disease. Background: About 40-85% of Parkinson's…Research Information Disclosure In The PPMI Study: Development Of A Disclosure Process
Objective: The Parkinson Progression Markers Initiative (PPMI) is a multinational, longitudinal observational study that collects clinical, imaging, biologic, and genetic data from participants with or…Advancing regulatory endorsed drug development tools in alignment with emerging biology: The Critical Path for Parkinson’s Consortium
Objective: To advance the regulatory maturity of drug development tools to support the newly proposed integrated staging of Neuronal Synuclein Disease (NSD-ISS) with focus on…Boosting Clinical Trial Power in Parkinson’s Disease with AI-Generated Digital Twins
Objective: To evaluate the incorporation of prognostic digital twins to enhance traditional clinical trials in Parkinson’s Disease (PD) for disease modifying therapies. We assess the…
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