Nigral Neuroinflammation and Dopaminergic Neurons in PD, MSA and PSP: A Comparative Clinicopathological Study
Objective: To investigate nigral neuroinflammatory markers and dopaminergic neuron counts in parkinsonian disorders, comparing their profiles across conditions. Background: In degenerative parkinsonian disorders, the primary…Utilization of Skin Punch Biopsy for the Diagnosis of Alpha-synucleinopathy in Clinical Practice
Objective: To understand the use of skin punch biopsies for diagnosis and management of α-synucleinopathy within a large medical system. Background: Skin punch biopsy has…Prediction of Time-to-Phenoconversion to Parkinsonism in Idiopathic REM Sleep Behavior Disorder (iRBD)
Objective: To develop a tool for the prediction of time-to-phenoconversion in individuals with iRBD during the prodromal stage of parkinsonism. Background: Parkinson’s disease(PD) and dementia…The impact of stimulation setting on Battery Longevity in Deep Brain Stimulation
Objective: This study aims to assess the estimated battery longevity and its determinants in Percept model of Deep Brain Stimulation (DBS) devices in patients diagnosed…Association between Parkinsonism, Parkinson’s Disease and Cognitive Impairment and Incidence of Dementia in People with Parkinsonism and Parkinson’s Disease in Latin America: A 10/66 Dementia Research Group Study
Objective: The study aimed to determine the cross-sectional and prospective associations between parkinsonism and Parkinson's disease with cognitive impairment and dementia in a large multi-country…Incident & Prevalent Dementia in Individuals with Parkinson’s Disease in the Framingham Heart Study
Objective: To examine incident and prevalent dementia cases in individuals with Parkinson's Disease (PD) within a longitudinal population-based study Background: Longitudinal studies have found that…Assessing the Impact of Deep Brain Stimulation on Cognitive Impairment in Parkinson’s Disease: a longitudinal study.
Objective: To longitudinally assess cognitive function post-DBS in Patients with Parkinson's Disease. Background: Parkinson's disease (PD) is a chronic neurodegenerative condition that primarily affects the…Transcutaneous tibial nerve stimulation for overactive bladder symptoms in Parkinson’s disease: results from a phase II randomised control trial (STRIPE)
Objective: To undertake a randomised control trial of transcutaneous tibial nerve stimulation (TTNS) delivered by Geko™ device for LUTS related to overactive bladder (OAB) symptoms…Association Between Motor Symptoms and Autonomic Dysfunction in De Novo Parkinson’s Disease: Insights into the Role of the Gut-Brain Axis
Objective: This retrospective study aimed to investigate the relationship between motor symptoms and autonomic dysfunction in patients with de novo Parkinson's disease(PD). Background: Dysautonomia in…Prodromal Parkinson’s disease in the general population
Objective: To investigate the diagnostic value of the MDS research criteria for the detection of the prodromal phase of Parkinson’s disease (PD) in the general…
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