Common and specific immediate effects in brain oscillations and motor symptoms of tDCS and tACS in Parkinson’s disease: A randomized controlled trial
Objective: We conducted the first randomized controlled trial (RCT) to compare the modulation of Parkinson's disease (PD) patients by tDCS and tACS. Background: PD entails…Characterisation of the Pattern of Daily Motor Fluctuations in Patients with Parkinson’s Disease and Early Motor Fluctuations: Findings from the Korean ADOPTION Study
Objective: To characterise the pattern of daily motor fluctuations in Korean patients with Parkinson’s disease (PD) and early motor fluctuations. Background: Patients with PD may…A matching-adjusted indirect comparison of efficacy and safety for safinamide versus rasagiline as adjunctive treatment to levodopa in Chinese patients with Parkinson’s disease
Objective: To compare efficacy and safety of safinamide and rasagiline as adjunctive treatment to levodopa in Chinese patients with Parkinson’s disease (PD) by matching-adjusted indirect…Motor Phenotype Changes over time in Parkinson’s Disease. A 5-year Follow-up Study
Objective: The objectives of this study are to describe the prevalence of different motor phenotypes (MP) in a cohort of Parkinson’s Disease (PD) patients, to…Developing a selection framework for digital measures of Parkinson’s disease progression for the EJS ACT-PD trial
Objective: To develop a selection process for digital measures (DMs) to include as exploratory outcome measures of Parkinson’s disease (PD) progression in a platform disease…A Study to Evaluate the Efficacy and Safety of Intravenous Prasinezumab in Participants with Early Parkinson’s Disease (PADOVA): Rationale, Design, and Baseline Data
Objective: To evaluate the effect on slowing motor progression and the safety of prasinezumab, a humanized monoclonal antibody targeting aggregated alpha-synuclein, in individuals with early…Mortality Rate, Cause of Death and Factors Associated with Mortality in Late Stage Parkinson’s Disease
Objective: The aim was to carry out a long-term follow-up of a cohort of patients in late stage Parkinson’s disease (PD) with focus on mortality…Formulations and Assessments of Intra-nasal noses to brain curcumin delivery using reversible nanoparticles for Parkinsonism treatment: A Preclinical Approach
Objective: Parkinson's disease (PD) is a prevalent neurological illness that is typified by bradykinesia, postural instability, tremor, and stiffness. An increasing body of research suggests…Oropharyngeal Adverse Events in Parkinson’s Patients with Motor Fluctuations Treated with Apomorphine Sublingual Film
Objective: This post-hoc analysis of Study CTH-301 assessed the occurrence of oropharyngeal treatment-emergent adverse events (TEAEs) in patients with Parkinson’s disease included in this study.…Pharmacokinetics of Levodopa after Subcutaneous bolus delivery of foslevodopa/foscarbidopa
Objective: To characterize the pharmacokinetics (PK) of levodopa (LD) after bolus delivery of foslevodopa/foscarbidopa Background: Foslevodopa/foscarbidopa is a soluble formulation of LD/CD prodrugs delivered as…
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