MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Parkinson’s"

  • 2025 International Congress

    The Relationship among Depression, Self-Esteem, and Sense of Coherence in Patients with Parkinson’s Disease

    Y. Ando, T. Yamawaki, Y. Ueki, S. Okuda, N. Tsuchikawa, K. Keiji, T. Kobayashi (HIroshima, Japan)

    Objective: This study aimed to examine the relationship among depression, self-esteem, and sense of coherence (SOC) in patients with Parkinson's disease (PD) and to propose…
  • 2025 International Congress

    Modified Timed Up and Go test as a marker for motor improvement in advanced Parkinson’s disease after in-patient multimodal intensive neurorehabilitation and care

    M. Mccrossin, F. Avantaggiato, E. Cipparonne, L. Rubin, A. Di Rocco (Glen Cove, USA)

    Objective: To determine if a modified Timed Up and Go (TUG) test can be used to monitor motor improvement in patients with Parkinson’s disease (PD)…
  • 2025 International Congress

    Immediate Impact of Whole-Body Vibration on Backward Walking in Individuals with Parkinson disease

    A. Boddy, K. Barta, M. Flores, K. Sawyer, L. Perry, A. Campbell (Waco, USA)

    Objective: Determine the immediate impact of performing partial squats using whole-body vibration (WBV) versus level surface on backward walking velocity in People with Parkinson Disease.…
  • 2025 International Congress

    Trends on recruitment and retention in Parkinson’s Disease modification trials

    D. Hengartner, R. Palacio, J. Garinger, A. Lysandropoulos (Durham, USA)

    Objective: To identify the most common causes of participant’s screen failure (SF) and drop-out (DO) in Phase 2 and 3 Disease Modification Therapy (DMT) trials…
  • 2025 International Congress

    A Proof-of-Concept Study of TR-012001, a Nasal Levodopa, in Patients With Parkinson’s Disease With OFF Episodes, Without Dopa Decarboxylase Inhibitor

    M. Nomoto, H. Yabe, R. Ando, Y. Sumiyoshi, T. Akagi, R. Ise, Y. Akiyoshi, C. Date, S. Nakano, R. Suzuki, Y. Sonoda, S. Haruta, S. Kanazashi, A. Mori, I. Nagata (Tokyo, Japan)

    Objective: To evaluate the safety, tolerability, levodopa pharmacokinetics, and exploratory efficacy of TR-012001 in Parkinson’s disease (PD). Background: TR-012001 is a novel investigational prefilled nasal…
  • 2025 International Congress

    LRRK2 Pathway Inhibition By NEU-411, a Potent, Selective, CNS-Penetrant LRRK2 Inhibitor In Healthy Participants

    C. Wong, S. Dheerendra, T. Dang, F. Nahab, J. Zheng, S. Savage, Z. Pei, C. Wynne, S. Jackson, L. Desnoyers (South San Francisco, USA)

    Objective: The aim of this work was to evaluate LRRK2 pathway modulation by the potent, selective, CNS-penetrant LRRK2 inhibitor NEU-411 in healthy adults and elderly…
  • 2025 International Congress

    EJS ACT-PD: An Ongoing Initiative to Support Innovation and Sustainability of a Multi-Arm, Multi-Stage Platform Trial for Parkinson’s Disease

    G. Mills, C. Gonzalez-Robles, M-L. Zeissler, O. Bandmann, R. Barker, J. Carpenter, S. Collins, J. Duffen, S. Gandhi, K. Mcfarthing, A. Schapira, A. Schrag, C. Carroll, T. Foltynie (London, United Kingdom)

    Objective: To provide continued consortium expertise to provide ongoing innovation and long-term sustainability in a multi-arm, multi-stage (MAMS) disease modification trial for Parkinson’s disease (PD).…
  • 2025 International Congress

    Trans-Spinal Theta Burst Magnetic Stimulation Enhances Treadmill Training Effects on Gait in Parkinson’s Disease

    L. Lopes, J. Oliveira, A. Costa-Ribeiro, K. Monte-Silva, C. Souza, M. de Melo, M. Gomes, L. Shirahige, R. Albuquerque, R. Carra, C. Tanaka, E. Barbosa, D. de Andrade, R. Cury (Sao Paulo, Brazil)

    Objective: To investigate whether intermittent Theta Burst Trans Spinal Magnetic Stimulation(iTB–TsMS) enhance treadmill training benefit on gait function, freezing of gait(FoG), other motor symptoms and…
  • 2025 International Congress

    A retrospective study on thyroid dysfunction mimicking Parkinsonian symptoms

    D. Mukhammedaminova, L. Kenjaeva (Tashkent, Uzbekistan)

    Objective: This retrospective study analyzes outcomes of nine patients (three females, six males) admitted to the endocrinology department from 2020 to 2024. Initially diagnosed with…
  • 2025 International Congress

    Effect of Continuous Subcutaneous Infusion of Foslevodopa/Foscarbidopa on motor fluctuations, dyskinesia, and sleep; subjective vs. PKG watch recordings.

    M. Bradley, E. Donlon, A. Gallagher, C. O'Keefe, J. Inocentes, F. Ruggieri, R. Reilly, R. Walsh, T. Lynch, C. Fearon (Dublin, Ireland)

    Objective: To evaluate the impact of continuous subcutaneous infusion (CSCI) of foslevodopa/foscarbidopa on bradykinesia, dyskinesia, and sleep quality using self-reported Hauser diaries and Parkinson’s KinetiGraph…
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