Alterations in neuron-derived exosomal cargo in Parkinson Disease
Objective: The main objectives are 1) the confirmation of exosome isolation, based on iPSC-derived midbrain neuron model, 2) the identification of α-synuclein cargo of PD-patient…Type 2 diabetes-associated transcriptomic changes in Parkinson’s disease and non-neurodegenerative control brains.
Objective: To evaluate the effect of type 2 diabetes (T2D) on gene transcription in Parkinson’s disease (PD) and non-neurodegenerative control brains. Background: People with T2D…Neurophysiological and Clinical Effects of Low-intensity Transcranial Ultrasound of the Motor Cortex in Parkinson’s Disease
Objective: Evaluate the neurophysiological and clinical effects of transcranial ultrasound stimulation (TUS) of motor cortex (M1) in PD patients. Background: Low-intensity TUS is a novel,…Validity and reliability of the Thai version of the Freezing of Gait Questionnaire (FOG-Q) in individuals with Parkinson’s disease (PD)
Objective: To evaluate the validity and reliability of the Thai version of FOG-Q (Thai FOG-Q) in individuals with PD. Background: Freezing of gait (FOG) is…Exploratory delayed-start analysis of PASADENA evaluating the efficacy of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease
Objective: To evaluate the effect of prasinezumab on motor progression and motor complications in early-stage Parkinson’s disease (PD) using an exploratory delayed-start analysis of Part…Association of creaky voice with motor severity in Parkinson’s disease using an automated algorithm.
Objective: We characterized creaky voice in Parkinson’s disease (PD) and evaluated the association of this acoustic phenomenon with motor and cognitive status. Background: Creaky voice (“vocal fry”)…GP2: Growing a research community in the Parkinson’s disease genetics field through training and networking
Objective: To establish a virtual ‘center of excellence’ with resources and expertise to serve the training needs of the Global Parkinson’s Genetics Program (GP2; www.gp2.org)…DIFFERENCE IN MOTOR AND NONMOTOR SYMPTOMS BETWEEN YOUNG AND LATE ONSET PARKINSON`S DISEASE
Objective: To evaluate difference in prevalence of nonmotor symptoms and severity of autonomic and motor symptoms between patients with young (YOPD) and late onset (LOPD)…Non-dopaminergic system is related with motor reserve in Parkinson’s disease
Objective: To find related brain structures with the motor reserve in Parkinson's disease (PD). Background: There is a discrepancy between the severity of parkinsonism and dopaminergic…Effect of Subthalamic Nucleus Stimulation (STN-DBS) on psychosocial function using the scale “SCOPA-PS” in patients with Parkinson’s Disease at the National Institute of Neurology and Neurosurgery in Mexico during 2007 to 2020.
Objective: To determine the psychosocial function of patients with Parkinson's disease, with history of subthalamic nucleus stimulation, using the SCOPA-PS questionnaire. Background: Parkinson's disease (PD)…
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