Neurophysiological architecture of visual categorization in early Parkinson’s disease with minor hallucinations
Objective: To explore the neurophysiological dynamics of visual categorization in Parkinson’s disease (PD) with minor hallucinations. Background: Different hypotheses have been proposed for visual hallucinations…Jumping to Conclusions bias, psychosis and impulsivity in early stages of Parkinson’s disease
Objective: The aim was to explore the correlations between Jumping to Conclusions (JtC) tendency and neuropsychiatric features in patients with early Parkinson’s disease (PD). Background:…Innovating Clinical Trial Design to Accelerate Assessment of Disease-Modifying Treatments for Parkinson’s: The EJS ACT-PD Initiative
Objective: To design an optimal multi-arm, multi-stage (MAMS) platform trial for disease-modifying therapies (DMTs) in Parkinson’s disease (PD). Background: The current clinical trials process cannot…Development of therapeutic substances for the disassembly of α-synuclein aggregates as disease-modifying treatment of synucleinopathies
Objective: Development of high-affinity ligands to α-synuclein (α-syn) for a therapeutic approach aiming for the disassembly of α-syn aggregates as a disease-modifying treatment of synucleinopathies.…Novel RAB39B stop mutation in patient with typical Early-Onset Parkinson’s disease
Objective: N/A Background: RAB proteins are small guanosine triphosphatases (GTPases) that are ubiquitous and expressed in all cell types regulating vesicular transport and intracellular membrane…Screening and Treatment of Depression in Parkinson’s Disease Within Movement Disorders Centers
Objective: Implement depression screening using a validated instrument for people with Parkinson’s (PWP) as part of standard of care in the specialist movement disorders setting…Zonisamide in advanced Parkinson’s disease: a randomized placebo-controlled study in Egyptian population
Objective: To investigate safety and efficacy of ZNS on motor ,non motor symptons and quality of life in advanced PD in egyptian populatiin Background: Zonisamide…Navigating Open Science in Canada with the Canadian Open Parkinson Network
Objective: The Canadian Open Parkinson Network (C-OPN) is a pan-Canadian initiative that bridges people, data and resources to accelerate new discoveries in the field of…Comparison of original and revised versions of the University of Pennsylvania Smell Identification Test
Objective: To assess agreement between the original and revised versions of the University of Pennsylvania Smell Identification Test (UPSIT). Background: Recently published age/sex-specific UPSIT percentiles,…Modeling Parkinson’s disease progression accounting for the effect of symptomatic treatments in the Parkinson’s Progression Markers Initiative study
Objective: To explore the natural history of Parkinson’s disease (PD) accounting for the effect of symptomatic treatments on progression by modeling the time course of…
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