A Retrospective Comparison of Multiple Approaches to LFP-guided and Imaging Guided Contact Selection in Subthalamic Deep Brain Stimulation for Parkinson’s Disease
Objective: To retrospectively compare several local field potential (LFP)-guided approaches for contact selection with an imaging-guided strategy and monopolar reviews, using long-term motor outcome as…α-Synuclein biomarkers in prodromal synucleinopathies: a systematic review and meta-analysis.
Objective: To quantify the diagnostic accuracy and predictive performance of α-synuclein biomarkers in isolated REM sleep behaviour disorder (iRBD), pure autonomic failure (PAF), and idiopathic…Restless leg syndrome in Parkinson’s disease: A systematic review on the prevalence, demographic, clinical profile and diagnostic criteria
Objective: This systematic review aims to estimate the pooled prevalence of restless leg syndrome (RLS) in Parkinson’s disease (PD) and illustrate the updated understanding of…Correlation between handwriting and cognitive function in patients with Parkinson’s disease
Objective: To investigate whether handwriting performance in Parkinson’s disease (PD) patients is associated with neuropsychological function. Background: PD patients typically present impaired handwriting with slower…GLP-1 Receptor Agonists in Movement Disorders: From Parkinson’s Disease to the Broader Spectrum — Mechanisms, Evidence, and Future Directions
Objective: To provide a comprehensive narrative review of the mechanistic rationale and clinical evidence for GLP-1 RA use across the spectrum of movement disorders, including…A case of monotherapy with intracerebroventricular anaerobic dopamine allows complete control of Parkinson’s disease symptoms
Objective: To investigate the safety and efficacy of continuous circadian and personalized intracerebroventricular (i.c.v.) administration of anaerobic dopamine (A-dopamine) in Parkinson's disease patients refractory to…The Spectrum of Praxis Impairments in Patients with Parkinson’s Disease
Objective: Our study aims to examine the state of praxis within the structure of motor impairments in patients with Parkinson's disease (PD). Background: PD is…STEM-PD: An open-label phase I/II trial of transplanted human pluripotent stem cell-derived dopaminergic progenitor cells in Parkinson’s disease
Objective: The STEM-PD trial evaluates safety, tolerability, and feasibility of intraputaminal transplantation of STEM-PD, a dopaminergic(DA) progenitor product derived from a clinical-grade human embryonic stem…Clinical-Genealogical Analysis of Parkinson’s Disease
Objective: The aim of the study is to investigate the clinical and genealogical features of Parkinson's disease. Background: More than 90% of Parkinson's disease (PD)…PEST-PD: Preliminary Findings from an Ongoing Longitudinal Observational Study for Prodromal Parkinson’s disease in farmers exposed to pesticides.
Objective: To compare the risk for prodromal Parkinson's disease (PD) in subjects exposed and non-exposed to pesticides Background: Farmers may have an elevated risk of…
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