Smell as a Diagnostic Signature: Systematic Review and Meta-Analysis of UPSIT Accuracy in Distinguishing Parkinson’s Disease from Essential Tremor
Objective: To evaluate the diagnostic performance of the University of Pennsylvania Smell Identification Test (UPSIT) in differentiating Parkinson’s disease (PD) from essential tremor (ET) using…Effects of Modafinil on Motor and Non‑Motor Outcomes in Parkinson’s Disease: A Meta‑Analysis of Randomized, Placebo‑Controlled Trials
Objective: To determine the efficacy and safety of modafinil on motor and non-motor outcomes in Parkinson’s disease (PD) using evidence exclusively from randomized placebo‑controlled clinical…Smell Testing in The Global Parkinson’s Genetics Program (GP2)
Objective: To identify cohorts with existing olfactory data within the Global Parkinson’s Genetics Program (GP2, http://gp2.org/). To support harmonisation across cohorts and facilitate future expansion…Why Context Matters: The Influence of Medication and Environment on Real-World Gait in People with Parkinson’s Disease
Objective: To quantify the extent to which contextual factors explain the variability in real-world gait outcomes in people with Parkinson’s disease (PwP) using machine learning…High-Intensity Multimodal Training Through Group-Based Weighted Dance for Parkinson’s Disease: A Feasibility Study
Objective: To examine the feasibility and preliminary effects of a 4-week high-intensity multimodal training (HIMT) program [1], delivered through group-based weighted dance, for people with…Real-World Clinical Outcomes of Adaptive versus Continuous Deep Brain Stimulation in Early-Stage Parkinson’s Disease: A Systematic Review and Meta-Analysis of 2024-2025 Trials
Objective: To evaluate the comparative efficacy, safety, and energy efficiency of adaptive deep brain stimulation (aDBS) versus continuous deep brain stimulation (cDBS) in Parkinson’s disease…Classification of Fallers in Parkinson’s Disease Through Machine Learning Based Feature Analysis
Objective: To develop and validate a machine learning model integrating clinical and gait data to identify key clinical markers associated with faller status in Parkinson’s…Menstrual Cycle Influence on Parkinson’s Disease Symptoms in Women with Early-Onset
Objective: To characterize the prevalence of menstrual cycle–related symptom fluctuations in women with early-onset Parkinson's disease (EOPD). Background: Hormonal fluctuations during the menstrual cycle may…Exploring a Milestone-Based Approach as an Outcome Measure for Disease-Modifying Parkinson Disease Trials
Objective: To replicate a composite milestone(CM) approach in a range of Parkinson Disease(PD) studies(observational, clinical trials) over a long time period(up to 12 years). To…The Clinical and Biological effects of a Whole Foods and Plant-Based Dietary Intervention in Parkinson’s Disease
Objective: The Plants for Parkinson trial aims to investigate whether prolonged adherence to a plant-based and whole foods-derived dietary pattern can alleviate motor- and gastrointestinal…
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