Meta-optimization to select stimulation settings for deep brain stimulation in Parkinson’s disease
Objective: The objective is to develop an algorithmic approach for selecting deep brain stimulation (DBS) settings for Parkinson’s disease (PD) and other movement disorders more…The cortical thickness signature and future phenoconversion in isolated REM-sleep behavior disorder: a longitudinal analysis
Objective: To develop an imaging biomarker predicting subtype-specific phenoconversion in isolated REM sleep behavior disorder (iRBD), we aim at identifying MRI-driven cortical thickness signature in…Directional DBS – Early experiences with “Current steering” in India
Objective: Deep Brain Stimulation using directional leads is relatively recent in India. We present our early experiences with the same. Background: Deep brain stimulation (DBS)…Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…IgG to neurotensin in blood of Parkinson’s disease patients
Objective: The aim of the study was measurement of IgG to NT in blood plasma of Parkinson's disease patients. Background: Neurotensin (NT) is a 13-amino-acid…The profile of dysautonomia in the early stages of Parkinson’s disease and multiple system atrophy: the importance of using the SCOPA-AUT scale
Objective: To examine the profile of autonomic dysfunction and the utility of the SCOPA-AUT scale in distinguishing patients with early Parkinson's disease (PD) and MSA-parkinsonism (MSA-P)…Longitudinal Analysis of the Corticospinal Tract in Parkinson’s disease Patients
Objective: To assess longitudinal diffusion tensor imaging differences between PD patients in 8 corticospinal tract segments. Background: Parkinson’s disease (PD) is clinically defined by the presence…Preliminary real-world surgical data collection in RAD-PD
Objective: To describe surgical practices in a cohort of patients with Parkinson’s disease (PD) undergoing deep brain stimulation (DBS). Background: DBS is well-established to improve…A Novel Parkinson Shoe: A potential treatment of Unresponsive Freezing of Gait in Parkinson’s Disease Patients
Objective: To explore the effect of the novel PD shoe on FOG and gait parameters in PD patients with unresponsive FOG. Background: Freezing of gait (FOG) is…Interventions to Improve Gait in Parkinson’s Disease: A Systematic Review of Randomised Controlled Trials and Network Meta-Analysis
Objective: This systematic review and network meta-analysis sought to quantify and rank interventions targeting gait in PD. Background: Among the disabling motor symptoms of Parkinson’s…
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