Factors that negatively impact the sexual function of women living with Parkinson’s disease
Objective: To investigate the impact of motor and non-motor alterations and couple adjustment on sexual function in women living with PD in Brazil. Background: Among…LRRK2 Inhibition by BIIB122: Trial designs for two efficacy and safety studies in Parkinson’s disease patients with and without LRRK2 mutations (Lighthouse and Luma)
Objective: Describe Luma and Lighthouse, two studies that investigate efficacy and safety of BIIB122, a LRRK2 inhibitor. Background: Increased LRRK2 kinase activity has been linked…Level of glial neurotrophic factor in the blood plasma depending on the duration of Parkinson’s disease
Objective: To study the level of glial neurotrophic factor in the blood plasma depending on the duration of PD. Background: Study of the biochemical aspects…Establishing and validating 1-methyl-2-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced zebrafish model of Parkinson’s disease
Objective: The current study aims to establish a zebrafish model of PD using MPTP neurotoxin and the validation of the MPTP effect through swimming behavior…Telephone nursing care for Parkinson’s patients: one-year experience in a tertiary referral hospital in Italy
Objective: To establish a telephone nursing service led by a Parkinson Disease Nurse Specialists (PDNS) and monitor the one-year experience in a tertiary referral Italian hospital (Movement…The Journey Of Levodopa Treatment in Parkinson’s disease
Objective: This study aims to relook the journey of levodopa in the treatment of Parkinson’s disease. Background: Levodopa has been used in the treatment of…Abnormal fractional anisotropy of the tremor network in tremor dominant Parkinson’s disease and Essential tremor plus syndrome
Objective: To evaluate alterations in fractional anisotropy (FA) of the basal ganglia-thalamocortical (BGTC) and cerebello-thalamocortical (CTC) network in tremor dominant Parkinson’s disease (TDPD) and essential…Predictive factors for a favorable STN-DBS outcome in Parkinson’s Disease: the role of axial symptoms
Objective: We sought to identify and weight clinical and demographic factors predicting bilateral STN-DBS outcomes. Background: DBS is an established therapeutic option for treating PD…A systematic review on physical health education interventions for people with Parkinson’s: content, impact and implementation considerations across Parkinson’s trajectory
Objective: To examine the content of education interventions that promote physical activity (PA) behavior in PwP, and to assess their effectiveness on physical and psychosocial…Determination of glycine transporter 1 levels with [3H]-NFPS binding in hemi-parkinsonian rats with L-DOPA induced dyskinesia
Objective: To determine the distribution of the glycine transporter 1 (GlyT1) in brain areas implicated in parkinsonism and L-3,4-dihydroxyphenylalanine (L-DOPA) induced dyskinesia in the 6-hydroxydopamine…
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