Physical exercise as a promising option for treating fatigue in Parkinson’s disease? Results of a systematic review and meta-analysis of non-pharmacological interventions
Objective: To give an update on randomized controlled trials (RCT) including non-pharmacological intervention approaches that examine effects on fatigue in people with Parkinson’s disease (PD).…Using mediation analysis to account for the effect of Parkinson’s Disease medications on disease progression
Objective: To explore the use of mediation analysis to incorporate L-dopa equivalent daily dose (LEDD) for disease progression of Parkinson’s Disease (PD) in a simulation…Open-label Extension Study of Long-term Safety and Tolerability of Foslevodopa/Foscarbidopa for Treatment of Advanced Parkinson’s Disease
Objective: To evaluate long-term safety/tolerability of foslevodopa/foscarbidopa (LDP/CDP) in patients with advanced Parkinson’s disease (aPD) in a phase 3 open-label extension (OLE) study. Background: LDP/CDP…A non-expensive bidimensional assessment can detect subtle alterations in gait performance in people in the early stages of Parkinson’s disease
Objective: To investigate the effectiveness of a two-dimensional gait assessment to identify the decline in gait performance associated with Parkinson's disease progression Background: Gait is…Continuous estimation of Parkinson’s on-off states using wearable devices
Objective: Utilize passive, continuous data from mobile and wearable devices to estimate on-off states in Parkinson’s patients. Background: The Hauser motor diary is often used…Detecting Changes in Parkinson’s Motor Symptom Patterns Using Wearable Devices
Objective: Evaluate mobile application and wearable device for detecting clinically significant changes in Parkinson's motor symptoms. Background: Monitoring motor and non-motor symptoms in Parkinson's disease…Incidence and Predictors of Axial Postural Abnormalities in Parkinson disease: data from the PPMI cohort
Objective: We aim to evaluate the incidence of axial postural abnormalities in patients with Parkinson’s disease (PD) and analyze their demographic and clinical predictors. Background:…Analysis of excessive daytime sleepiness and clinical findings in Parkinson’s disease
Objective: To explore clinical biomarkers associated with excessive daytime sleepiness (EDS) using a real-world cohort database of Parkinson’s disease (PD). Background: Although evidence for current…In vivo proteomic investigation of deeply phenotyped parkinsonian syndromes for biomarkers of differential diagnosis
Objective: To investigate deeply-phenotyped cohorts of parkinsonian syndromes using proteomic technologies for identification of biomarkers for differential diagnosis Background: Proteomic technologies like Olink® Explore 3072…Effects of a nurse-led Advance Care Planning and Care Coordination intervention in Parkinson’s Disease – patient and family caregiver perspectives from a multicentre European study
Objective: To investigate an Advance Care Planning (ACP) and care coordination intervention from the perspective of people with Parkinson's disease (PwPD) and their family caregivers…
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