Predictive factors of LCIG infusion therapy adherence – a single-center study of 103 consecutive LCIG patients
Objective: The objectives of this study were to find predictive factors for early dropout from levodopa-carbidopa intestinal gel (LCIG) infusion in advanced Parkinson’s disease (PD)…Novel approach to MDS-UPDRS monitoring in clinical trials: Longitudinal Item Response Theory Models
Objective: Using the unique advantages of Item Response Theory (IRT), we developed unidimensional and multidimensional models to investigate non-tremor and tremor MDS-UPDRS Part 3 changes…Investigation of the consultation status and clinical symptoms of patients with Parkinson’s disease after the spread of COVID-19
Objective: This study investigated the consultation status and clinical symptoms of patients with Parkinson’s disease (PD) after the coronavirus disease 2019 (COVID-19) pandemic. Background: Due…Shannon entropy: a novel tool for assessing pentagon drawing in Parkinson’s disease
Objective: We used a digitizing tablet during PCT as a potential tool for assessing early cognitive deficits in PD yet without major cognitive impairment. We…The retrograde procedural memory in people with Parkinson’s disease with or without freezing of gait – a cross-sectional study.
Objective: To investigate the retrograde procedural memory in people with typical Parkinson’s disease (PwP) with or without freezing of gait (FOG). We hypothesized that the…Digenic R1441G-LRRK2 and Parkin mutations in Parkinson’s Disease: first clinicopathological case report.
Objective: To report a clinicopathological case of digenic PD with R1441G- LRRK2 and PRKN mutations. Background: Digenic inheritance of R1441G-LRRK2 and PRKN mutation is extremely…SHBG, and possibly testosterone, are associated with the risk for Parkinson’s disease among women: a Mendelian randomization approach
Objective: To assess the association between Sex Hormone Binding Globulin (SHBG), Testosterone, and Estradiol with Parkinson's disease (PD). Background: Sex hormones may protect dopaminergic neurons,…Remote assessment of prodromal Parkinson’s disease in a LRRK2 G2019S cohort
Objective: To compare remote application of the Movement Disorder Society (MDS) prodromal Parkinson’s disease (PD) criteria to expert clinical determination of possible parkinsonism in a…The role of amylin in Parkinson´s disease neurodegenerative process
Objective: We investigate the functional interaction between two amyloidogenic (amylin and synuclein) proteins as a potential mechanism for neurodegeneration in Parkinson disease (PD). Background: PD…Age-dependent multisystem parkinsonian features in a novel neuromelanin-producing transgenic mouse model
Objective: We aim to characterize the consequences of age-dependent intracellular neuromelanin accumulation in catecholaminergic neuronal populations to understand the relationship between this process and the…
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