Clinical and Psychophysiological Characteristics of Chronic Pain in Parkinson’s Disease: Pain Phenotypes, Central Sensitization, and Quality of Life
Objective: To assess clinical characteristics and pain phenotypes in PD patients with different types of chronic pain, to assess the severity of central sensitization and…Can Voice Therapy Improve Swallowing in Advanced Parkinson’s Disease? A Comparison of SPEAK OUT!® Outcomes in Patients With Deep Brain Stimulation and Medical Therapy
Objective: To evaluate a 12-session SPEAK OUT!® program's effects on swallowing in advanced PD, comparing outcomes between medication-only and DBS-treated patients. Background: Oropharyngeal dysphagia is…Preservation of Cognition Following Intravenous Mesenchymal Stem Cell Therapy in Parkinson’s Disease: Secondary Analysis of a Randomized Trial
Objective: To evaluate longitudinal changes in global cognition following intravenous allogeneic bone marrow–derived mesenchymal stem cell (allo-hBM-MSC) therapy in Parkinson’s disease (PD). Background: Cognitive impairment…A Case Report: Optimising Motor and Non-Motor Control in Advanced Parkinson’s Disease: The Role of Foslevodopa/Foscarbidopa After Deep Brain Stimulation
Objective: To investigate the combined use of continuous subcutaneous foslevodopa/foscarbidopa and deep-brain stimulation in managing advanced Parkinsons Disease. Background: Continuous foslevodopa/foscarbidopa subcutaneous (SC) infusion has been shown…Virtual Reality–Based Rehabilitation for Freezing of Gait in Parkinson’s Disease: Implications for Cognitive–Motor Integration: A Systematic Review
Objective: To evaluate the effects of VR-based rehabilitation on freezing of gait and gait performance in individuals with PD and FOG. Background: Freezing of gait…Effect of subthalamic nucleus deep brain stimulation on heart rate variability in Parkinson’s disease
Objective: To characterize the effects of bilateral subthalamic nucleus deep brain stimulation (STN-DBS) on cardiac autonomic regulation at rest and during paced deep breathing in advanced…Dopamine Receptor Blocking Drug Exposure is Associated with Parkinson’s Disease
Objective: To test the hypothesis that dopamine receptor blocking agents (DRBAs) contribute to the later diagnosis of Parkinson’s disease (PD). Background: Recent evidence suggests that…Investigating Substantia Nigra Microstructural Integrity as a Potential Predictive Biomarker for Fall Burden in Parkinson’s Disease
Objective: Determine whether baseline Diffusion Tensor Imaging (DTI) measures of the substantia nigra (SN) predict fall incidence and burden in Parkinson’s disease (PD). Background: Degeneration of dopaminergic…Regional landscape of Parkinson’s disease: An update from the NeuRA Natural History of Parkinson’s Study
Objective: To characterise the epidemiology of Parkinson's Disease(PD) and compare risk factors/exposures between Regional and Metropolitan New South Wales(NSW). Background: The Natural History of PD…Robot-Assisted Transplantation of Hypoimmune iPSC-Derived Dopaminergic Progenitor Cells for PRKN-EOPD
Objective: This study aimed to evaluate the safety and preliminary efficacy of NCR201 transplantation in a PRKN-EOPD patient, providing a first proof-of-concept for this hypoimmune…
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