Sleep seasonality in alpha-synucleinopathies: a comparative study with non-neurological sleep disorder patients
Objective: To assess month of the year related changes in polysomnography (PSG) data in patients with alpha-synucleinopathies. Background: Season of the year related changes in…NLX-112 has favorable safety and tolerability and displays efficacy against levodopa-induced dyskinesia (LID) in Parkinson’s disease (PD)
Objective: To assess the safety, tolerability and preliminary efficacy of NLX-112 (a.k.a. befiradol) in patients with moderate to severe LID in PD: a randomized, double-blind,…Alzheimer’s Disease Co-pathology and its Influence on Biofluid Biomarkers in Autopsied Subjects from the PPMI Study
Objective: To examine the relationship between biofluid biomarkers and post-mortem pathological findings in autopsied subjects from the Parkinson’s Progression Marker Initiative (PPMI). Background: The PPMI…Glial neurotrophiz factor as a differential marker of Parkinson`s disease and vascular parkinsonism
Objective: To analysis of glial neurotrophic factor content in blood serum of patients with PD and VP. Background: Parkinson's disease (PD) and vascular parkinsonism (VP)…Does fatigue in Parkinson’s disease impact one’s physical function in daily live?
Objective: To investigate fatigue at baseline and 3.5 years later and its association with balance and gait over time. Background: In Parkinson’s disease (PD), fatigue…Identifying delirium in Parkinson’s: evaluation of existing tools and measures
Objective: To evaluate the diagnostic accuracy of tools to identify delirium in inpatients with Parkinson’s disease (PD). Background: Delirium is a serious acute state of…Deep brain stimulation and fusion technologies: a synthesis study
Objective: The major thrust is analyzing the large amounts data computationally generated and synthesizing it into useful systems-wide models of biological processes. Background: It is…Using Long read sequencing to identify complex structural variants in PRKN-PD
Objective: Identify complex structural variants in PRKN gene from Parkinson’s disease patients. Background: PRKN is the most frequent causative gene in young onset Parkinson's disease…Randomized, waitlist-controlled trial of Karate Intervention to Change Kinematic Outcomes in PD (KICK OUT PD)
Objective: To test the adherence to and efficacy of twice-weekly karate classes for people with mild to moderate Parkinson’s Disease (PD) on quality of life…Pallidal or subthalamic DBS for advanced Parkinson’s disease in the era of high-resolution MRI
Objective: We aimed to assess outcome of GPi-DBS and STN-DBS implanted based on high-resolution MRI. Background: Both GPi-DBS and STN-DBS are effective for treatment of…
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