Motor skills of walking in Parkinson’s disease: towards a better understanding of the cognitive abilities implicated in F8WT.
Objective: to evaluate disease related and cognitive features involved in motor skills of walking in people with Parkinson’s disease (PWP). Background: curved path walking and…Systematic review of cognitive subtypes derived from data driven approaches in Parkinson’s disease
Objective: To consolidate the current literature pertaining to cognitive subtypes derived using data-driven methods in Parkinson’s Disease (PD). Background: Recent application of the Mild Cognitive…Interrogating Parkinson’s disease associated mutations at single cell resolution
Objective: To uncover potentially causative Parkinson’s disease (PD) somatic mutations in post-mortem substantia nigra pars compacta (SNpc) tissues from sporadic PD patients using single cell…GBA variants in a multi-ethnic Parkinson’s disease (PD) cohort in Malaysia
Objective: To investigate the frequency of Glucocerebrosidase (GBA) gene variants in a multi-ethnic Parkinson’s disease (PD) cohort in Malaysia. Background: GBA variants have been associated…Reduced serum PRDX3 levels are a biomarker for Asian LRRK2 carriers in Parkinson’s disease
Objective: We measured serum peroxiredoxin-3 (PRDX3) levels in Parkinson’s disease (PD) patients with and without LRRK2 risk variants, hypothesizing that PD LRRK2 carriers will show…Fatty acids and Glucocerebrosidase activity as potential biomarkers of stearyl-CoA desaturase inhibition; an observational study of inter and intraday variation in healthy volunteers and patients with Parkinson’s disease
Objective: This study aimed to assess the naturally occurring levels and variation in plasma fatty acids (FA) and ceramide metabolism in healthy volunteers (HV) and…Biomarker candidates – Peptides identified to be differentially abundant in cerebrospinal fluid of patients with Parkinson´s disease
Objective: The aim of this study was to identify cerebrospinal fluid peptides that are differential in the cerebrospinal fluid of patients with Parkinson´s disease. Those…Aberrant dopamine transporter and functional connectivity patterns in LRRK2 and GBA non-manifesting carriers
Objective: We aimed to study the association between presynaptic striatal dopamine uptake and functional connectivity (FC) patterns among healthy first-degree relatives of PD patients with…Parkinson Disease with, but not without, Cognitive Decline Reveals Advanced Brain Aging
Objective: To investigate “brain age” in Parkinson disease (PD) with and without cognitive decline, and its correlation with motor and cognitive performance. Background: Although brain…Baseline and six months change in cortical perfusion in a mesenchymal stem cell trial for Parkinson’s disease
Objective: Quantify cortical perfusion at baseline and six months after a single infusion of allogeneic bone marrow-derived mesenchymal stem cells (allo-hMSC) in relation to demographic…
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