Single-cell characterization of patient midbrain tissue reveals tissue remodeling and glial activation in Parkinson’s disease
Objective: We aim to characterize the contribution of each midbrain cell type to PD pathology, and to identify cell types associated with genetic PD-risk variants.…Quality of life changes after subthalamic stimulation for Parkinson’s disease depend on nonmotor and motor symptoms clusters
Objective: To analyze quality of life (QoL) changes after subthalamic stimulation (STN-DBS) based on a short list of baseline nonmotor and motor symptoms in Parkinson’s…Neural activity during turning in Parkinson’s: influence of dual-task and freezing
Objective: To examine the neural activity during turning in Parkinson’s disease (PD). Background: Turning is impaired in PD with links to freezing of gait (FOG)…A Potential Cluster Near Site of Dry Cleaning Contamination
Objective: To characterize specific health outcomes of people with potential exposure to chemicals used in dry cleaning. Background: Trichloroethylene (TCE) is a chlorinated solvent used…Value of Archimedes spiral in tremor.
Objective: Retrospective study whose main objectives is to describe the characteristics of Archimedes spiral (AS) (presence of axis and direction) and to relate them to…“Belly Dance Tremor” – Hip and Truncal tremor in Parkinson’s disease
Objective: To report unusual presentation of Young-Onset Parkinson’s disease with disabling hip and trunk rest tremor resembling “belly dance”. Background: Proximal tremor is not commonly…A Mixed Methods Study on the Impact of Reading the Graphic Memoir My Degeneration: A Journey Through Parkinson’s on Patients with Parkinson’s Disease
Objective: To explore the impact of reading a graphic memoir on patients’ knowledge, mental health, and attitudes about living with Parkinson Disease (PD). Background: In…Feasibility of telephonic voice samples to remotely monitor people with Parkinson’s disease residing in medically underserved rural regions
Objective: To explore the feasibility of collecting voice samples using digital voicemail in People with Parkinson’s disease (PwPD). Background: For many PwPD, the increased adoption…Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson’s disease
Objective: Herein we evaluated the regional selectivity of presynaptic striatal dopaminergic denervation associated with RBD in drug-naive early PD. Background: REM sleep behavior disorder (RBD)…Can membrane association of α-synuclein aggregates lead to stress in the astrocytic endoplasmic reticulum?
Objective: To study the association extracellularly added wildtype-WT and A30P/A53T mutant α-synuclein aggregates with the astrocytic membrane and to evaluate the effect of these peptides…
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