The cortical thickness signature and future phenoconversion in isolated REM-sleep behavior disorder: a longitudinal analysis
Objective: To develop an imaging biomarker predicting subtype-specific phenoconversion in isolated REM sleep behavior disorder (iRBD), we aim at identifying MRI-driven cortical thickness signature in…Directional DBS – Early experiences with “Current steering” in India
Objective: Deep Brain Stimulation using directional leads is relatively recent in India. We present our early experiences with the same. Background: Deep brain stimulation (DBS)…Increased alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease
Objective: To assess glucocerebrosidase and alpha-synuclein level in primary macrophages derived from patients with Parkinson’s disease with and without GBA1 mutation. Background: Parkinson’s disease (PD)…IgG to neurotensin in blood of Parkinson’s disease patients
Objective: The aim of the study was measurement of IgG to NT in blood plasma of Parkinson's disease patients. Background: Neurotensin (NT) is a 13-amino-acid…The profile of dysautonomia in the early stages of Parkinson’s disease and multiple system atrophy: the importance of using the SCOPA-AUT scale
Objective: To examine the profile of autonomic dysfunction and the utility of the SCOPA-AUT scale in distinguishing patients with early Parkinson's disease (PD) and MSA-parkinsonism (MSA-P)…Longitudinal Analysis of the Corticospinal Tract in Parkinson’s disease Patients
Objective: To assess longitudinal diffusion tensor imaging differences between PD patients in 8 corticospinal tract segments. Background: Parkinson’s disease (PD) is clinically defined by the presence…Preliminary real-world surgical data collection in RAD-PD
Objective: To describe surgical practices in a cohort of patients with Parkinson’s disease (PD) undergoing deep brain stimulation (DBS). Background: DBS is well-established to improve…A Novel Parkinson Shoe: A potential treatment of Unresponsive Freezing of Gait in Parkinson’s Disease Patients
Objective: To explore the effect of the novel PD shoe on FOG and gait parameters in PD patients with unresponsive FOG. Background: Freezing of gait (FOG) is…A prospective, controlled study of subthalamic stimulation in Parkinson’s disease: quality of life outcome at the 5-year follow-up
Objective: To compare the 60-months quality of life (QoL) effects of subthalamic stimulation (STN-DBS) to standard-of-care oral/transdermal medical therapy (MED) in Parkinson's disease (PD). Background:…Impact of dopamine replacement therapies on MDS-UPDRS II
Objective: To estimate the longitudinal effect of different dopamine therapies on the Movement Disorder Society-Sponsored Unified Parkinson's Disease Rating Scale Part II (MDS-UPDRS II) among…
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