MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Parkinson’s"

  • 2025 International Congress

    Evaluation of the Pharmacodynamic Effects of BIIB122/DNL151 in Participants with LRRK2 mutation-driven Parkinson’s disease (BEACON Study)

    J. Kluss, S. Huntwork-Rodriguez, D. Jennings, S. Ota, R. Maciuca, J. Alkabsh, S. Davis, J. Suh, M. Schwarzschild, K. Fraser, R. Llorens-Arenas, C. Ho, P. Chin (South San Francisco, USA)

    Objective: To characterize the biomarker effects of BIIB122/DNL151 in participants with LRRK2 pathogenic mutations diagnosed with Parkinson’s disease (LRRK2-PD). Background: BIIB122/DNL151 is a CNS-penetrant small…
  • 2025 International Congress

    Plasma Protein Profiles Reveal Distinct Molecular Signatures in Parkinson’s Disease and Multiple System Atrophy

    SJ. Chung, S. Jo, I. Jang, J. Lee, M. Choi, E. Lee (Seoul, Republic of Korea)

    Objective: We aimed to identify distinct plasma proteins in patients with Parkinson’s disease (PD) and multiple system atrophy (MSA) and evaluate their associations with disease…
  • 2025 International Congress

    A Prospective, Observational Study to Identify Biomarkers in Parkinsonian Syndromes (proATYP).

    M. Makrygianni, D. Potamianou, T. Pipikos, M. Xilouri, C. Mourmouris, A. Sarafi, L. Florentin, M. Stamelou (Athens, Greece)

    Objective: This is a prospective observational study to identify biomarkers in parkinsonian syndromes. Background: Parkinson’s disease (PD) and atypical parkinsonian syndromes namely progressive supranuclear palsy…
  • 2025 International Congress

    Glossography – a novel, computer-vision based technique for assessing and treating involuntary tongue movements in dyskinetic episodes in Parkinson’s disease

    M. Brzezicki, M. Palczynski, E. Pilchowska-Ujma, O. Szymańska-Adamcewicz, N. Pawlak, P. Lesniak, S. Jurga (Oxford, United Kingdom)

    Objective: To develop and evaluate a novel deep learning-based computer vision approach for tracking tongue movements in Parkinson's disease (PD) patients with levodopa-induced dyskinesias to…
  • 2025 International Congress

    Alpha-Synuclein Preformed Fibrils Increase the Frequency of CXCR3+ B-cells in Early-stage Parkinson’s Disease Patients

    H. Hong, M. Dean, D. Standaert, H. Qin, E. Benveniste (Birmingham, USA)

    Objective: To investigate the effect of a-Syn Preformed Fibrils (PFF) on CXCR3 expression on B-cells in Parkinson’s Disease (PD) patients at early (E-PD, diagnosed less…
  • 2025 International Congress

    Determinants of Cognitive Progression in Parkinson’s Disease: A Machine Learning Approach

    AJ. Hernández-Medrano, A. Cervantes-Arriaga, MF. Medina-Pérez, D. Ulloa-Hernández, MF. Velasco-Delgado, GA. Martin-Mafud, AE. López-Lobato, D. Náfate-Wences, M. Rodríguez-Violante (Mexico City, Mexico)

    Objective: To identify clinical and sociodemographic factors associated with cognitive decline (CD) in PD using a Random Forests model, classifying people with PD (PwP) into…
  • 2025 International Congress

    The Role of Neuropsychiatric Symptoms in the Diagnosis of Early Parkinson’s Disease: a Systematic Review

    J. Vasconcelos Silva, G. Guindani Maia, MA. de Brito, AC. Prudente (Porto Alegre, Brazil)

    Objective: This study aims to evaluate the role of neuropsychiatric symptoms in the diagnosis of Early Parkinson's Disease. Background: Neuropsychiatric symptoms (NPS) are important and…
  • 2025 International Congress

    Duration of Illness and Response to Pimavanserin in Parkinson’s Disease Psychosis: Post-Hoc Analysis of Clinical Trial Data

    K. Dashtipour, A. Espay, M. Tagliati, G. Brunson, X. Feng, N. Rashid, L. Chrones (Loma Linda, USA)

    Objective: To examine individual responses to pimavanserin in patients with Parkinson’s disease psychosis (PDP) initiating treatment <6 vs ≥6 months and <12 vs ≥12 months…
  • 2025 International Congress

    Characteristics of Visual Hallucinations in Lewy Body Dementia

    Y. Luo, RY. Lo, J. Wang (Hsinchu, Taiwan)

    Objective: To investigate the risk and the content of visual hallucination (VH) among patients with Lewy body dementia (LBD) within the cultural background of Taiwan.…
  • 2025 International Congress

    The Impact of Depression on Information Storage, Consolidation and Evocation Processes in a Group of Patients Diagnosed with Idiopathic Parkinson’s Disease without Dementia by Deep Brain Stimulation. Descriptive study of the ESDEPARK Scale.

    C. Alberto Hurtado-González, J. Felipe Ayala-Rico, S. Ospina-Otalvaro, P. Andrea Gutiérrez-Lenis, A. Lucumi Moreno, M. Cañas-Lucendo, D. Reyes-Torres, L. Villegas-Trujillo, S. Ordoñez-Cure, K. Alejandro Rivera-Quintero (Cali, Colombia)

    Objective: To identify the clinical correlation between neurocognitive functioning in memory and depressive symptomatology in patients with IPDWD, assessed by a new scale (ESDEPARK) that…
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