Heterozygous mutations in the Parkin gene – two different presentations of Parkinson’s disease
Objective: The main objective of this work is to present two Parkinson's disease (PD) patients with heterozygous mutations in the Parkin gene (PARK – parkin)…A Single-Centre Canadian Study of Disparities in Access to Deep Brain Stimulation for Movement Disorders
Objective: To identify disparities in gender and ethnicity among deep brain stimulation (DBS) patients to reduce differences in access to care by implementing strategies to…POOR SLEEP QUALITY AND OBESITY IN PATIENTS WITH PARKINSON’S: PRELIMINARY RESULTS OF A COHORT STUDY
Objective: Describe the prevalence of overweight and obesity in patients with PD who have poor quality sleep. Background: Sleep disturbances are common and often severe…Merging global cohorts of manifesting and non-manifesting carriers of pathogenic variants in known Parkinson’s disease genes
Objective: To create a global cohort of manifesting and non-manifesting carriers of pathogenic variants in known monogenic Parkinson's disease (PD) genes, such as LRRK2, PRKN, and PINK1, to better…What, when and how should the information on iRBD and risk of Parkinson’s disease and related conditions be communicated?
Objective: To investigate what, when and how patients with iRBD would like to receive information regarding the potential future implications of having iRBD, once diagnosis…Improving the design of clinical trials in early-stage Parkinson’s disease by using the estimand framework
Objective: To show how the estimand framework can be used to improve design of clinical trials testing treatments in early-stage Parkinson’s disease (PD). Background: The…Validation of a wireless Home-Based Sleep Laboratory for assessment of sleep-related disorders in Parkinson’s disease
Objective: To examine the validity of a new wireless wearable system which measures EEG, EOG and sEMG for the assessment of sleep and sleep related…The effect of rasagiline on nocturnal hypokinesia: the analysis of the Nocturnal Hypokinesia Questionnaire (NHQ)
Objective: To identify the effect of rasagiline on nocturnal hypokinesia based on Nocturnal Hypokinesia Questionnaire (NHQ). Background: Nocturnal hypokinesia refers to the difficulty or the…The role of cortical and subcortical structures in maintaining efficient network topology in Parkinson’s disease
Objective: To assess the relative importance of cortical and subcortical nodes and their connections in maintaining efficient structural connectome topology in Parkinson's disease (PD). Background:…Dried blood and plasma spots for the measurement of neurofilament light chain and inflammatory cytokines in patients with REM sleep behaviour disorder
Objective: The objective of this study was to investigate the relationship between plasma and dried blood/ plasma spot measurements of inflammatory markers (IFN-ɣ, IL-1β, IL-6,…
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