Central fatigue and glutamatergic overactivity in Parkinson’s disease: possible impact of safinamide
Objective: The aim of the present study was to test the hypothesis that central fatigue in Parkinson’s disease (PD) could be related to high levels…Levodopa-carbidopa intestinal gel (LCIG) as an add-on therapy to deep brain stimulation (DBS) for managing progressive symptoms of advanced idiopathic Parkinson’s disease during the COVID-19 pandemic: Case Report
Objective: To report the use of levodopa-carbidopa intestinal gel (LCIG) as an additional therapy for the treatment of motor fluctuations in a patient with advanced…Feasibility of using mobile technology for aerobic exercise management in people with Parkinson’s disease
Objective: To examine the usability of a smartwatch heart rate monitor for monitoring aerobic exercise compliance during a 6-month brisk walking program, and to evaluate…SelfCog®: a digitized cognitive battery to classify Parkinson disease (PD) patients with or without Mild Cognitive Impairment (MCI)
Objective: We tested the performance of the SelfCog® to classify PD patients as MCI. Background: MCI is a strong risk factor of dementia in PD…Genetics Of Parkinson’s in India – Young Onset Parkinson’s Disease (GOPI-YOPD) : Genetics of Juvenile, Young and Early Onset Parkinson’s Disease
Objective: To determine the genetic and demographic patterns of juvenile-onset (JOPD, <20 years), young-onset (YOPD, 20-40 years), and early onset (EOPD, 40-50 years) Parkinson's disease…Clinical characteristics in de-novo PD patients with reversible vs. progressive cognitive dysfunction during long-term follow-up
Objective: To compare clinical and imaging features in de-novo Parkinson’s disease (PD) with stable, remitting, and non-remitting cognition over 5 years follow-up. Background: Mild cognitive…The Lion’s tail family: A Bavarian multiplex pedigree with pathologically confirmed multiple system atrophy and Parkinson’s disease with dementia
Objective: To characterize a North-Bavarian (Lion’s tail region) six-generation pedigree, including neuropathologically confirmed multiple system atrophy and Parkinson’s disease with dementia. Background: Multiple system atrophy…Case reports of first experiences worldwide with novel continuous oral levodopa dental pump in Parkinson’s Disease Patients
Objective: To assess the safety, tolerability, and pharmacokinetics (PK) of a novel continuous levodopa-carbidopa oral pump (LCOP) delivery system in patients with early PD. Background:…The relationship between sleep and Parkinson’s disease progression: A Mendelian Randomization study
Objective: The objective of the study was to determine the causality between sleep disorders and progression of motor and cognitive endpoints of Parkinson’s disease. Background:…Preliminary results on the cognitive profile in prodromal Parkinson’s disease – a prospective study
Objective: This study aims to investigate the cognitive profile in people with REM-sleep behavior disorder (RBD) and hyposmia, in a prodromal Parkinson’s disease (PD) cohort.…
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