- The role of network connectivity in shaping the progression of cortical atrophy in Parkinson’s diseaseObjective: We aimed to map the progression of cortical thinning and to test whether this pattern is constrained by network connectivity in the brain. Background:…
- Emotional stress exacerbates parkinsonian resting tremorObjective: To examine the role emotions may play in modulating the characteristics of parkinsonian resting tremor. Background: There is ample evidence showing cognitive stress can…
- Locus coeruleus volume is reduced in Parkinson disease-related orthostatic hypotension.Objective: To test whether structural pathology of the locus coeruleus (LC) is associated with orthostatic hypotension (OH) in Parkinson disease (PD). Background: OH is an…
- The prevalence of sarcopenia in Parkinson’s disease and related disordersObjective: To systematically review the prevalence of sarcopenia in Parkinson’s disease (PD) and atypical parkinsonian syndromes (aPS), how prevalence differs with PD stage and between…
- GASTROINTESTINAL SYMPTOMS ARE ASSOCIATED WITH LEFT PREDOMINANT DOPAMINE TRANSPORTER BINDING DEFICIT IN PARKINSON´S DISEASEObjective: To assess correlations between functional gastrointestinal (GI) symptoms and nigrostriatal dopamine transporter imaging asymmetry in Parkinson´s disease (PD) patients. Based on a theory that…
- Peripheral neuromodulation for the treatment of bladder symptoms associated with Parkinson’s diseaseObjective: To undertake a systematic review of the literature on peripheral neuromodulation techniques for the treatment of bladder symptoms in Parkinson’s disease (PD). Background: Bladder…
- Evidence of gut dysbiosis in treatment-naïve de novo Parkinson’s diseaseObjective: To determine the gut microbiome composition of treatment-naïve de novo Parkinson’s disease (PD) patients. Background: Over fifteen studies have independently demonstrated gut dysbiosis in…
- Effects of Angiotensin Type 1 Receptor Antagonists on Parkinson’s Disease Progression: an exploratory study in the PPMI databaseObjective: The objective of this study is to analyze the effect of exposure to AT1 receptor blockers (ARBs) and angiotensin-converting enzyme inhibitors (ACEIs) on the clinical…
- Transcranial direct current stimulation-related changes in postural responses to perturbations are not influenced by baseline clinical characteristics in Parkinson’s disease.Objective: To investigate the association between clinical characteristics and transcranial direct current stimulation (tDCS)-related changes in postural responses to external perturbations in people with Parkinson’s…
- Effectiveness of an intensive and structured therapy (LSVT-BIG) in comparison to conventional therapy for people with Parkinson’s disease in Singapore.Objective: The aim of the study was to investigate if Lee Silverman Voice Therapy BIG (LSVT)-BIG® programme was more effective than conventional physiotherapy for People…
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