Altered functional activity of the motor system related to ankle and hand movements in Parkinson’s disease: insights from functional MRI
Objective: Examine functional magnetic resonance imaging (fMRI) activity during hand and foot force production tasks in Parkinson’s disease (PD). Background: Previous MRI studies in PD…Longitudinal structural and functional brain alterations in Parkinson’s disease patients with freezing of gait
Objective: To investigate the cortical/subcortical grey matter (GM) changes and network functional alterations in PD-FoG patients, in PD developing FoG (PD-FoG-converters) and PD not developing…Progression of brain atrophy in Parkinson’s disease is shaped by connectome and local vulnerability
Objective: Using MRI data, the aim of this longitudinal study was to map the progression of brain atrophy over four years and relate it to…Inter-Electrode Distance influences the phase-amplitude coupling (PAC) of Bipolar Subthalamic Local Field Potentials Recordings in Parkinson’s Disease
Objective: This study aimed to assess phase-amplitude coupling (PAC) between two local field potential (LFPs) signals captured from both wide- and close-spaced contact pairs (i.e.…Enhanced arm swing improves Parkinson gait associated with EEG power modulations resembling those in healthy gait.
Objective: To examine whether enhanced arm swing improves Parkinsonian gait and explore the role of the supplementary motor area (SMA) in such an improvement. Background:…Dysphagia risk, respiratory muscle strength and maximal phonation time in elderly with Parkinson Disease in the initial stages
Objective: To analyze the risk of dysphagia, respiratory muscle strength (RMS) and maximal phonation time (MPT) in elderly with Parkinson's disease (PD) in the initial stages…Clinical Features Associated with Dysautonomia in Prodromal Parkinson’s Disease
Objective: To compare clinical features between those with and without dysautonomia in a cohort with other prodromal Parkinson’s disease (PPD) markers. Background: Dysautonomia has been…Clinical predictors of impulsive and compulsive behavior after subthalamic stimulation in Parkinson’s disease
Objective: Exploring predictive clinical factors of subthalamic stimulation (STN-DBS) which affect impulsive and compulsive behavior (ICB). Background: ICB is frequently observed in Parkinson’s Disease (PD)…Reducing anxiety improves freezing of gait in Parkinson’s disease patients
Objective: Investigate the effect of reducing anxiety using a known anxiolytic, alprazolam, on FOG symptoms severity and frequency. This reduction, in turn, might reduce the…Cerebrospinal fluid levels of oxidative stress measured using diacron-reactive oxygen metabolites and biological antioxidant potential in patients with Parkinson’s disease and progressive supranuclear palsy
Objective: We aimed to evaluate cerebrospinal fluid (CSF) levels of oxidative stress (OS) and antioxidant potential using diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential…
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