Clinical Impact of Nicotine in Parkinson’s Disease: Evidence from Randomized Controlled Studies
Objective: To evaluate the effects of nicotine versus placebo in Parkinson’s disease (PD). Background: Nicotine may influence dopaminergic and non‑dopaminergic pathways relevant to PD. While…Association of Quality of Life with Risk Markers and Prodromal Signs of Parkinson’s Disease in the Population-Based Healthy Brain Ageing Study
Objective: To understand which factors associated with the risk of developing Parkinson's disease (PD) influence quality of life (QoL) in a cohort from the European…Posterior tibial nerve Stimulation in the management of Urinary Disorders in Parkinson’s Disease Experience of the National Hospital Center of Pikine
Objective: Evaluate the efficacy of posterior tibial nerve stimulation in the management of LUTS in patients with PDCompare posterior tibial nerve stimulation to medication Background:…Enteric Alpha-Synuclein Pathology in Early-Onset Parkinson’s Disease and an Incidental Case in Spinocerebellar Ataxia Type 6
Objective: This study aimed to investigate Alpha-synuclein (AS) accumulation in the gastrointestinal (GI) tract of patients with early-onset PD (EOPD). Background: AS accumulation is found…Gut Barrier Failure In Parkinson Disease: Reduced Colonic Resilience In Moderate Disease And Spontaneous Pan-Intestinal Leak In Severe Disease
Objective: To determine whether intestinal barrier dysfunction in Parkinson disease (PD) is stage-specific by assessing baseline epithelial permeability and resilience to inflammatory and microbial stressors.…Evaluating YouTube as a source of health information on Parkinson’s disease
Objective: This study aimed to evaluate the quality, reliability, and engagement characteristics of YouTube videos on Parkinson's disease using standardized assessment tools. Background: Parkinson’s disease…Baseline assessment of nigrostriatal integrity via VMAT2 PET in participants with Parkinson’s disease from the BIIB122/DNL151 LUMA Phase 2b study
Objective: Evaluate nigrostriatal integrity using vesicular monoamine transporter 2 (VMAT2) PET in participants with early-stage PD enrolled in the LUMA study. Background: LUMA is a…Patient-centered Parkinson’s services and integrated primary care in southern Ghana: patient and caregiver perceptions from a cross-sectional survey
Objective: To evaluate patients’ and caregivers’ perceptions of patient-centered care for persons with Parkinson’s disease (PwPD) across three healthcare facilities in southern Ghana, and to…The Nature of autonomic dysfunction and its relationship with motor symptoms in Drug-Naive Parkinson’s Disease Patients: Korean Cohort Data
Objective: We aimed to characterize the domain-specific distribution of autonomic symptoms in newly diagnosed, drug-naive PD and to investigate whether distinct autonomic patterns are associated…Validation of Augmented Reality–Based Speech Biomarkers for Objective Detection and Monitoring of Parkinson’s Disease and Atypical Parkinsonian Syndromes
Objective: To validate the feasibility and diagnostic potential of an offline, head-mounted augmented reality (AR) system for automated extraction of acoustic and temporal speech biomarkers in…
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