Parkin Mutation and Deep Brain Stimulation
Objective: To investigate the clinical features of Parkin mutated patients who undergone subthalamic brain stimulation (DBS group) and pharmalogically treated only (Non-DBS group). Background: The…HYPERSEXUAL DISORDER IN GBA-ASSOCIATED PARKINSON’S DISEASE: CASE REPORT
Objective: To describe a patient with PD and hypersexual disorder carrying a GBA variant. Background: Compulsive sexual behavior occurs in 4% of patients with Parkinson’s…The MJFF Global Genetic Parkinson’s Disease Research Resource
Objective: To establish a comprehensive research and clinical trial-ready resource of centers working with individuals with monogenic Parkinson’s Disease (PD). Background: As gene-targeted therapies are…The gut microbiome in Parkinson’s disease: longitudinal insights into disease progression and the use of device-assisted therapies.
Objective: We investigated the temporal stability of gut microbiome (GM) profiles from Parkinson’s disease (PD) patients initiating device-assisted therapies (DAT) and in a separate cohort…Neurogenetic Traits Outline Vulnerability to Cortical Disruption in Parkinson’s Disease
Objective: In this study, we characterized the brain topological intersection between propagating connectivity networks in healthy controls (HC) and Parkinson’s disease (PD) participants and gene…Dynamic functional connectivity changes in Parkinson’s disease patients with REM sleep behavior disorder
Objective: Our aim was to explore dynamic network connection changes in PD patients with RBD. Background: Rapid eye movement (REM) sleep behavior disorder (RBD) is…Characteristics of the amyloid beta networks in Parkinson’s disease patients: a PPMI study
Objective: The impact that amyloid beta (Aβ) accumulation in the brain has on the progression of Parkinson’s disease (PD) pathology is complex and poorly understood…Altered Resting-state Neural Activity in Parkinson’s Disease with Depression: a controlled study based on original meta-analysis results
Objective: Depression is a common non-motor symptom in Parkinson’s disease (PD), while its underlying pathophysiology remains unclear. Previous functional magnetic resonance imaging (fMRI) studies reported…Locus coeruleus degeneration associated with less levodopa responsiveness in Parkinson’s Disease
Objective: We aimed to explore the relationship between LC degeneration and levodopa responsiveness in Parkinson’s Disease (PD) patients in vivo. Background: Widely divergent responsiveness of…High intensity exercise improves Sleep EEG Delta Power in Parkinson’s Disease
Objective: This novel study tests the hypothesis that 16 weeks of high-intensity exercise rehabilitation combining resistance training plus body-weight interval training, compared with a sleep…
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