DBS Directional programming – Institution based study of programming in PD and ET patients
Objective: To examine the use of Deep Brain Stimulation (DBS) directional programming in Parkinson Disease (PD) and Essential Tremor (ET) patients Background: DBS and its utility…Metadata standards to support deployment of Digital Health Technologies in Clinical Trials in Parkinson’s Disease (PD)
Objective: A metadata framework for Digital Health Technologies (DHT) to support enhanced regulatory maturity, and to facilitate standardization and harmonization of data collection Background: DHTs…Effect of dopaminergic treatment on digital sensor features in Phase II PASADENA Part 1 in early Parkinson’s disease
Objective: To characterize the sensitivity of smartphone and -watch sensor features to levodopa and dopamine agonist (DA-Tx) treatment. Background: Digital health technology tools (DHTTs) enable…Are physiotherapists reliable in their scoring of freezing of gait?
Objective: To determine the reliability of freezing of gait scoring through post-hoc video analysis in raters with a physiotherapy background. Background: Freezing of gait affects…Early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia: A Population-based Study (2010-2015).
Objective: To examine the incidence, clinical features, and survival of early-onset Dementia with Lewy Bodies and Parkinson’s Disease Dementia (DLB/PDD) (≤55 years of age) in…Reproductive factors and risk of Parkinson’s disease in women: preliminary results from the French prospective cohort E3N.
Objective: Objective: To evaluate whether reproductive factors and use of exogenous hormones are associated with the risk of Parkinson’s disease (PD) in women. Background: Background:…Impact of extended quarantine during the COVID-19 pandemic on Parkinson’s disease (PD) patients.
Objective: To determine the impact of extended quarantine during the COVID-19 pandemic in PD patients. Background: Due to the Covid-19 pandemic, various types of social…Terminal Choking in Parkinson’s Disease
Objective: To establish whether choking is a frequent cause of death in Parkinson’s Disease (PD), if this is a feared consequence of PD in patients/caregivers…Efficacy of opicapone according to different levodopa daily intakes in Parkinson’s disease patients with motor fluctuations
Objective: To evaluate the efficacy of opicapone (OPC) in Parkinson’s disease (PD) patients with motor fluctuation according to different levodopa daily intakes. Background: OPC proved…Randomized, Placebo-Controlled Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of ABBV-0805, an Anti-Alpha-Synuclein Monoclonal Antibody in Healthy Subjects
Objective: To evaluate the safety, tolerability, pharmacokinetics (PK), and immunogenicity of ABBV-0805 following administration of single ascending doses of ABBV-0805, administered as intravenous (IV) infusions…
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