Low Frequency Directional Deep Brain Stimulation of the Cuneiform Nucleus for Levodopa-Resistant Freezing of Gait: Six-Month Outcomes.
Objective: This is a prospective, open-label, single-arm study to assess safety and efficacy of cuneiform(CnF) deep brain stimulation(DBS) in Parkinson's disease(PD) patients with levodopa-refractory freezing…Intraoperative deep brain stimulation intrinsic lead migration
Objective: To characterize the intrinsic deep brain stimulation (DBS) lead migration as it relates to different deep brain targets. Background: Effective DBS relies on careful…Distinguishing DBS and Non-DBS Parkinson’s Patients Using Recurrence Plots and Vision Transformers
Objective: To introduce an innovative method for distinguishing gait patterns in Parkinson’s Disease (PD) patients with medical or surgical treatment and healthy controls, by exploiting…Prodromal Clinical Markers of Parkinson disease in patients with Gaucher disease and their parents
Objective: To determine the presence of prodromal markers of Parkinson’s disease (PD) in Gaucher disease (GD) patients and their parents. Background: GBA gene mutation is…The Effects of Non-pharmacological Treatments for Parkinson’s Disease Sleep Disorders：A Systematic Review and Meta-Analysis
Objective: This meta-analysis aimed to assess the clinical efficacy of various non-pharmacological therapies for PD sleep disorders (PDSD) to inform treatment strategies. Background: Sleep disorders…Sex variations in non-motor symptoms (pain, fatigue, and nausea) in Parkinson’s disease patients: An analysis from the Mexican Parkinson’s Research Network
Objective: To compare pain, fatigue and nausea variables between sexes to see if there is a significant difference. Background: Patients with PD present motor and…Assessment of the Impact of Environmental Factors on Disease Progression in Parkinson’s Disease
Objective: This study evaluated the impact of environmental factors on the progression of Parkinson’s Disease (PD) in Texas using a claims-based algorithm to identify severity…Seed-based Metabolic Networks and Time Series Variation based on Functional [18F]-FDG PET in Parkinson’s Disease
Objective: To analyse seed-based metabolic networks and time series variation in Parkinson’s disease with and without mild cognitive impairment based on functional PET (fPET) Background:…Dietary and Environmental Risk factors of Parkinson’s Disease: An integrated study combining Network Pharmacology and Molecular Docking Analyses
Objective: This large-scale case-control study using network pharmacology and molecular docking, aimed to identify dietary and environmental risk factors of Parkinson’s disease (PD). Background: PD…Towards automated deep brain stimulation programming using neurophysiology and artificial intelligence
Objective: To develop a machine learning (ML) algorithm capable of predicting the optimal deep brain stimulation (DBS) contact based on neurophysiology. Background: DBS is an…
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