Differential Effect of Dopaminergic Treatment on Bradykinesia Features and Limb-kinetic Apraxia in Parkinson’s Disease
Objective: To investigate the differential effects of dopaminergic therapy on bradykinesia and limb-kinetic apraxia in PD patients using kinematic analysis. Additionally, transcranial magnetic stimulation (TMS)…Decoding Parkinson’s Progression: Longitudinal Volumetric MRI Biomarkers in Prodromal and Clinical Stages
Objective: This study investigates MRI volumetric analysis via VBM as a biomarker for early PD detection, focusing on structural alterations in deep gray matter regions…Boosting the LTP-like Plasticity Effect of Intermittent Theta-burst Stimulation with Gamma Transcranial Alternating Current Stimulation improves Bradykinesia in Parkinson’s Disease
Objective: We investigated whether transcranial alternating current stimulation (tACS) applied at the gamma frequency (γ) frequency on the primary motor cortex (M1) improves long-term potentiation…Semi-quantitative Evaluation of Midbrain Accumulation in 123I-FP-CIT SPECT in Parkinson’s disease and Parkinsonian Syndromes
Objective: To establish a method for evaluating midbrain accumulation of 123I-FP-CIT SPECT and assess its ability to differentiate between Parkinson’s disease (PD) and Parkinsonian syndromes…Cerebral Glucose Metabolic Features of GBA-Parkinson’s Disease as a window into cognitive impairment
Objective: to investigate cerebral glucose metabolism via fluorodeoxyglucose positron emission tomography (FDG-PET) and its correlation to clinical features in Parkinson’s disease (PD) patients with GBA1…Novel Parkinson’s Disease Genetic Risk Factors Within and Across European Populations
Objective: To assess genome-wide genetic risk for Parkinson’s disease (PD) within and across genetically determined European ancestries (European, Ashkenazi Jewish, Finnish, and Icelandic). We conducted…Hispanic Recruitment to PD GENEration at Columbia University
Objective: To evaluate the effect of having a Hispanic, Spanish-speaking research coordinator on recruitment of Hispanic and Latinx people with Parkinson's disease to the PD…A unique genetic duality: GAK and SCN4A Mutations in Myasthenic Syndrome and Early-Onset Parkinsonism in a Peruvian woman: A Case Report
Objective: To present the first genetically characterized non-linear summative damage characterized case resulting in early-onset parkinsonism associated with congenital myasthenia Background: The GAK (Cyclin G…Gene-Caffeine Interaction in Parkinson’s Disease: A Case-Control Study of Alpha-synuclein SNPs
Objective: Investigating the interaction between genetic susceptibility and caffeine intake in modulating Parkinson’s disease (PD) risk. Background: PD arises from a complex interplay of genetic…Oculomotor Differences in PARK2 PD: a Study of Structured and Unstructured Eye Movements in an Irish Genetic Cohort
Objective: To identify and measure how eye movements differ between biallelic PARK2 carriers, carriers of a single PARK2 variant and non-carriers using structured and unstructured…
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