A Double-Blind, Cross-Over Pilot Study Comparing Adaptive Deep Brain Stimulation (aDBS) to Conventional DBS in Parkinson’s Disease
Objective: To compare the efficacy of adaptive deep brain stimulation (aDBS) to conventional DBS (cDBS) in Parkinson’s disease through a double-blind, cross-over pilot study. Background:…Increasing Physical Activity in Parkinson’s Disease Via a Remotely Deployed Gamification Intervention
Objective: To determine feasibility and estimate effect of a remote behavioral intervention on daily steps and motor symptoms in Veterans with PD Background: Many types…Efficacy and safety of Rotigotine Extended-Release Microspheres in Early Parkinson’s Disease
Objective: To assess the efficacy and safety of Rotigotine extended-release microspheres (LY03003) in patients with early Parkinson's disease Background: Treatment that provides a continuous flow of…Exploring minzasolmin effect on digital measures captured by the Verily Study Watch in a subset of the ORCHESTRA trial participants
Objective: To investigate the progression over time and the effect of minzasolmin on digital outcomes collected in ORCHESTRA (NCT04658186). Background: Minzasolmin is an oral small…Continued Evaluation of Bemdaneprocel Following a Phase 1 Study for Parkinson’s Disease: Outcomes Through 3 Years
Objective: To report the safety and clinical outcomes of bemdaneprocel in participants with Parkinson’s disease (PD) through 3 years post transplantation. Background: Bemdaneprocel is an…Does the cerebellum compensate to enable motor learning in Parkinson’s Disease?
Objective: To test the causal relation between cerebellar function and learning in PD. Background: Neuroimaging studies reveal that people with Parkinson’s disease (PwPD) exhibit increased…Treatment Of Advanced Parkinson’s With Levodopa–Entacapone–Carbidopa Intestinal Gel – Impact On Dyskinesia
Objective: To evaluate the effect of long-term treatment with levodopa–entacapone–carbidopa intestinal gel (LECIG) infusion on daily time with dyskinesia in people with advanced Parkinson’s disease…Safinamide as an Adjunct Therapy for Motor Symptoms and ON-Time Extension in Parkinson’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Objective: To evaluate the efficacy of safinamide as an adjunct therapy in improving motor symptoms and extending ON-time in patients with Parkinson’s disease (PD). Background:…A case of Parkinson’s Disease whose Daily Levodopa/Carbidopa Intestinal Gel dose has been determined by her spouse and prevented Long-term Fluctuations
Objective: To present a case of Parkinson’s disease (PD) whose daily levodopa/carbidopa intestinal gel (LCIG) dose has been determined by her spouse and prevented long-term…Mucuna pruriens for FOG in Parkinson’s disease, Do we have a solution for this trivial problem?
Objective: To study the effects of Mucuna Pruriens when administered via inhalation route, to alleviated symptoms of Parkinson's disease most importantly freezing of gait. Background: Mucuna…
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