Multiparametric Prediction of Mild Cognitive Impairment in Parkinson’s Disease Using a Combination of Structural and Functional MRI Measures
Objective: To investigate whether the multiparametric combination of structural and functional (fMRI) neuroimaging parameters improves the prediction of mild cognitive impairment (MCI) in Parkinson's disease…Impact of Aquaporin-4 polymorphisms on Glymphatic Function and Motor Symptoms in Parkinson’s Disease
Objective: This study aims to investigate whether single-nucleotide polymorphisms (SNPs) of the Aquaporin-4(AQP4) gene were related to abnormal protein accumulation (α-synuclein), glymphatic dysfunction (DTI-ALPS), and…Whole Genome Sequencing of an Early-onset Malaysian Parkinson’s Disease Cohort
Objective: To investigate the genetic causes of Malaysian early-onset Parkinson’s disease (EOPD) patients with whole genome sequencing (WGS). Background: EOPD (age of diagnosis ≤50 years)…Familial parkinson disease A comparative study between LRRK2 and PINK 1 mutations
Objective: Describe the clinical phenotypes of monogenic forms of PD linked to LRRK2 and PINK1 mutations with a view to a comparative study between the…Retinal Structural Changes in Parkinson’s Disease: insight into GBA1-Related PD and non-mutated PD
Objective: The study aims to explore differences in retinal thickness between GBA1-related Parkinson Disease (GBA1-PD) and non-mutated PD (NM-PD) and to analyze correlations between clinical…Association Analysis Between Genotypes and Disease Progression in Parkinson’s Disease
Objective: To investigate the relationship between genetic subtypes and disease progression in Early-Onset Parkinson’s Disease (EOPD) . Background: Genetic factors play a critical role in…Exome-wide Burden Analysis Identifies SYT10 as a Genetic Modifier of GBA-PD in UK Biobank
Objective: Identify potential genetic modifiers of GBA1 risk on Parkinson’s disease (PD). Background: GBA1 is a common genetic risk factor for PD. GBA1-carrying PD cases…Deep Brain Stimulation and Lesional Surgery in Parkinson’s Disease: Our Experience in Santa Cruz de la Sierra, Bolivia
Objective: To evaluate the outcomes and complications of deep brain stimulation (DBS) and ablative surgery in patients with Parkinson’s disease (PD) in our center. Background:…Real-World USA Outcomes in Patients Implanted with DBS Systems Capable of Directionality and Multiple Independent Current Control
Objective: This on-going registry seeks to collect/analyze real-world clinical outcomes out to 2-years follow-up in levodopa-responsive Parkinson's disease (PD) patients implanted with Deep Brain Stimulation…Exploring pallidal gamma oscillations in Parkinson’s disease: A case report
Objective: To explore the presence and significance of finely tuned gamma in the globus pallidus internus (GPi) in Parkinson's disease (PD). Background: PD is a…
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