Genetic risk factors reduce the risk of diabetes mellitus in Parkinsons disease
Objective: To determine if LRRK2 variants are able to reduce the diabetes associated risk in Parkinsons disease Background: Leucine-rich repeat kinase 2 (LRRK2) mutations are…Fusion Learning with Attention-VAE Imputation for Mixed-Reality Multisensor Screening of Parkinson’s Disease
Objective: To evaluate whether a mixed-reality (MR) multisensor protocol combined with multimodal learning can discriminate Parkinson’s disease (PD) from healthy controls (HC) despite substantial missing…Interpretable AI for Quantitative Video-Based UPDRS Assessment of Hand Movements in Parkinson’s Disease
Objective: To quantify and compare the diagnostic contributions of the three standard MDS-UPDRS hand motor tasks using video-based assessment of bradykinesia in Parkinson's Disease (PD).…Improvement in Time Spent in OFF State and In the Functional Impact of Motor Fluctuations After Initiation with COMT Inhibitors in Parkinson’s Disease Patients with Early Wearing-Off: Results from the REONPARK Study
Objective: REONPARK study is an observational study conducted in Spain aimed at evaluating COMT inhibitors (iCOMT) tolerability and effectiveness in alleviating motor complications associated with…Dual device-aided therapy in advanced Parkinson’s Disease: combining bilateral deep brain stimulation and continuous subcutaneous foslevodopa/foscarbidopa Infusion
Objective: To describe our experience with dual device-aided therapies (DATs). Background: DATs for advanced Parkinson's disease (PD) include deep brain stimulation, continuous subcutaneous apomorphine infusion…Trans-Spinal Theta Burst Stimulation for Axial Symptoms in Parkinson´s Disease with Deep Brain Stimulation A Randomized Clinical Trial
Objective: The aim of this randomized, double-blind, sham-controlled trial was to evaluate whether trans-spinal theta burst magnetic stimulation could improve gait and balance outcomes in…Evaluating the GBA1 Intronic rs3115534-G PD Risk Variant in the PD GENEration Cohort
Objective: To investigate the frequency of a newly proposed PD risk factor in an intronic region of GBA1 in people with PD from the PD…Interplay of sex and GBA1 and LRRK2 genotype in Parkinson disease progression
Objective: To characterize disease heterogeneity and how sex impacts motor and cognitive progression class membership across genetic subgroups of GBA1, LRRK2, and idiopathic Parkinson disease (PD). Background: Autosomal…Efficacy of Repetitive Transcranial Magnetic Stimulation for Improving Motor Function in Parkinson’s disease; A Prospective, Multicenter, Crossover Study
Objective: We aimed to investigate the effect of repetitive transcranial magnetic stimulation (rTMS) on the improvement of motor function in patients with Parkinson’s disease (PD).…Long-term evolution of deep brain stimulation parameters in Parkinson´s Disease: A 6-year analysis.
Objective: Characterize longitudinal evolution of Deep Brain Stimulation (DBS) parameters in patients with Parkinson´s Disease (PD) over a 6-year period and evaluate stability of programming…
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