Can Technology Improve Service Delivery and Patient Outcomes in a Parkinson’s Speech and Language Therapy Clinic?
Objective: - Determine if Telea, an online care platform, can aid in efficiently addressing caseload needs and quantify clinical time saved through…Developing Composite Digital Measures for Tracking Parkinson’s Disease (PD) Progression using a Comprehensive Machine Learning-based Framework
Objective: To develop composite digital measures that could be used to track disease progression in early PD patients, and to determine whether they can outperform…Unlocking Movement Disorder Specialist Capacity and Mitigating Risk: a Platform Solution for Cost Reduction and Care Optimization in Parkinson’s Disease
Objective: Improve patient and physician care delivery experience through a technology-driven coaching and triage system. Background: Limited worldwide supply of Parkinson’s specialty care restricts access…A Device Agnostic Pipeline for Gait Detection and Assessment in Free-living and Clinical Environments
Objective: To provide a framework for a device agnostic gait analytics pipeline for standardizing and improving quantitative gait analysis using wearable sensors. Background: Gait impairments…GBA1 deficiency differentially affects endolysosomal trafficking in neurons and astrocytes
Objective: To characterize how GBA1 deficiency alters endolysosomal trafficking in astrocytes versus neurons. Background: Mutations in the gene glucosidase, beta acid 1 (GBA1) not only increase risk…PD GENEration: a genetic analysis beyond the classical 7 Parkinson’s disease genes
Objective: To expand the analysis of whole-exome sequencing (WES) data from patients with Parkinson’s Disease (PD) from the PD GENEration cohort. We looked for variants…Assessing Genome-wide Genetic Risk for Parkinson’s Disease in European Sub-Populations Across the Global Parkinson’s Genetics Program and National Biobanks
Objective: To assess genome-wide genetic risk for Parkinson’s disease (PD) within and across genetically determined European ancestries (European, Ashkenazi Jewish, and Finnish) from the Global…Genetic Analysis of Mendelian mutations in A Large Chinese Early-onset and Familial Parkinson’s Disease
Objective: This study aims to determine the mutation spectrum of Mendelian Parkinson’s disease (PD) genes and clinical features of mutation carriers within a cohort of early-onset…GBA Mutation Profile in Parkinson’s Disease: Insights from a Movement Disorders Center in Brazil
Objective: To identify the prevalence of pathogenic variants of the GBA1 mutation among patients with parkinsonism who have undergone genetic testing. Background: GBA gene encodes…Neural oscillatory dynamics in Parkinson disease and dystonia: Insights from EEG analysis
Objective: Changes in total power and entropy across raw data may enable the identification of comprehensive shifts in neural dynamics that may align with clinical…
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