LRRK2-Associated Parkinsonism With and Without In Vivo Evidence of Pathologic Alpha-Synuclein: Clinical and Biomarker Characterization
Objective: To compare clinical and biomarker features and rate of progression among LRRK2-associated parkinsonism cases with and without in vivo evidence of pathologic alpha-synuclein (asyn)…Functionality Analysis of Immunoregulatory Cells Stimulated with Dopaminergic Agonists in People Living with Parkinson’s Disease
Objective: To evaluate the effect of dopaminergic agonists (DA) on the activation and functionality of regulatory cells in People living with Parkinson's Disease (PwP). Background:…Early GBA-Related Parkinson’s Disease has a Distinct Clinical Phenotype and Cholinergic Innervation
Objective: This study aims to characterize the clinical features and cholinergic innervation of early Parkinson’s disease (PD) patients with GBA mutations (GBA-PD). Background: The GBA-PD…Synaptic Density Loss in Parkinson’s Disease Independent of Age: Preliminary Findings using [18F]SynVesT-1 PET Tracer
Objective: To determine whether synaptic density differs in the brain of people with Parkinson’s disease and healthy controls using the [18F]-SynVesT-1 PET tracer. Background: The…From Images to Insights: Subtyping Parkinson’s Disease Using Unsupervised Learning on MRI Data
Objective: To explore the heterogeneity of Parkinson's disease (PD) using unsupervised clustering of neuroimaging data, aiming to identify distinct subtypes based on volumetric features. Background:…Effects of Eromomastax speciosa in a Gastric Ulcer in a 6-hydroxydopamine (6-OHDA)-induced Rat Model of Parkinson’s Disease.
Objective: To investigate the extract of Eromomastax speciosa neuroprotective/gastroprotective potential in the indomethacin (IND)-induced gastric ulcer in a 6-hydroxydopamine (6-OHDA)-induced PD model. Background: Parkinson's disease…Arm swing deviations in patients with PD at different gait velocities
Objective: To assess bilateral arm swing (AS) and other gait parameters in patients with PD and healthy subjects (HS) at various gait speeds and to…Identification of reproducible metabolites for Parkinson’s Disease diagnosis using clinical data and computational modelling
Objective: To identify replicated metabolic markers of Parkinson’s Disease (PD) diagnosis from metabolomic studies and predict additional metabolic markers using computational metabolic modelling. Background: Reported metabolic markers of…Country and Sex Differences in Diagnosis Latency of Parkinson’s Disease in Latin American Populations
Objective: To compare the latency in Parkinson’s Disease (PD) diagnosis, from onset of motor symptoms to clinical diagnosis, by sex in Latin America. Background: In…Accelerometric Classification of Resting and Postural Tremor in Essential Tremor and Parkinson’s Disease
Objective: To investigate the predictive value of different accelerometry metrics for clinical ratings of Essential Tremor (ET) and tremor in Parkinson’s Disease (PD). Background: To…
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