Real-world variability in dosing of continuous subcutaneous foslevodopa/foscarbidopa infusion in advanced Parkinson’s disease: evidence from a single-center cohort
Objective: To evaluate dosing patterns, demographic characteristics, and safety outcomes in patients with advanced Parkinson's Disease (PD) treated with continuous subcutaneous foslevodopa/foscarbidopa infusion in routine…Real-World Clinical Experience With Continuous Subcutaneous Foslevodopa/Foscarbidopa Infusion In Advanced Parkinson’s Disease Patients With Mild Cognitive Impairment And History Of Psychosis
Objective: To describe the efficacy and safety of continuous subcutaneous infusion of foslevodopa/foscarbidopa (LDp/CDp) in advanced Parkinson’s disease (aPD) in routine clinical practice, focusing on…Response to symptomatic therapy in Primary Brain Calcification: a cohort survey
Objective: To assess therapy response in a PBC cohort Background: Primary Brain Calcification (PBC) is a neurodegenerative disorder characterized by calcium deposition in the brain…Differential Effect of MAO-B Inhibitors in GBA1 Carriers with Parkinson’s Disease Women vs Men
Objective: To investigate the longitudinal impact of MAOIs on motor progression among Parkinson's disease (PD) patients carrying GBA1 mutations, with an emphasis on sex-stratified clinical…Modulation of Excitatory/Inhibitory Neurotransmission via Targeting GABAA-Gephyrin Signaling: Integrated In-Silico, In-Vitro, and In-Vivo Evidence in Parkinson’s Disease Models
Objective: To evaluate the neuroprotective potential of wogonin in modulating excitatory–inhibitory neurotransmission via GABAA receptor and gephyrin signaling in rat models of Parkinson’s disease (PD).…Polypharmacy and its Impact in Individuals with Parkinson’s Disease: Theory- and Data-Driven Approaches
Objective: The aim is to explore the relationship between high prescription drug use (polypharmacy), and its unintended effects on individuals with Parkinson’s Disease (PD). Background:…Icariin, a Flavonoid from Epimedium, Confers Dopaminergic Neuroprotection and Neuromodulation in MPTP-Induced Parkinsonian Rats
Objective: The present study aims to evaluate the neuroprotective and neuromodulatory properties of icariin in an MPTP-induced Parkinsonian rat model. Background: Parkinson Disease (PD) is…Ambulatory PEMF stimulation using the DCcure device improves rest and postural tremor in patients with PD
Objective: To evaluate the effects of ambulatory transcranial pulsed electromagnetic field (PEMF) stimulation on rest and postural tremor in patients with Parkinson’s disease (PD). Background:…Anti Tremorgenic Properties Of Eslicarbazepine Acetate in The Harmaline Induced Tremor Mouse Model
Objective: This study evaluated potential anti-tremor properties of eslicarbazepine acetate (ESL), an antiseizure medication approved for treatment of focal-onset epilepsy, in the harmaline-induced tremor mouse…Intestinal Levodopa Infusion Therapies in Advanced Parkinson’s Disease: A 6-Month Prospective Cohort Study
Objective: To evaluate 6-month changes in motor and non-motor outcomes in patients with advanced Parkinson’s disease treated with levodopa/carbidopa intestinal gel (LCIG) or levodopa/entacapone/carbidopa intestinal…
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