MDS Abstracts

Abstracts from the International Congress of Parkinson’s and Movement Disorders.

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Articles tagged "Positron emission tomography(PET)"

  • 2019 International Congress

    Visual assessment of dopamine transporter imaging in normal pressure hydrocephalus

    KY. Kwon, H. Ju, K. Im, JY. Lee, MY. Ahn (Seoul, Republic of Korea)

    Objective: We aimed to investigate detailed analysis for striatal dopaminergic depletion in idiopathic normal pressure hydrocephalus (iNPH) with visual assessment. Background: Variable degree of parkinsonism…
  • 2019 International Congress

    Cortical cholinergic dysfunction correlates with microglial activation in the Substantia Innominata in patients with REM sleep behavior disorder

    K. Stær, A. Iranzo, M. Stokholm, K. østergaard, M. Eroles, M. Otto, K. Svendsen, A. Pla, D. Vilas, J. Santamaria, A. Møller, C. Gaig, P. Borghammer, D. Brooks, E. Tolosa, N. Pavese (Aarhus N, Denmark)

    Objective: To explore possible correlations between levels of microglial activation (neuroinflammation) in the Substantia Innominata (SI), the major source of cholinergic input to the cortex,…
  • 2019 International Congress

    Abnormal metabolic brain network in multiple system atrophy and progressive supranuclear palsy: a replication on a new European cohort

    T. Rus, E. Rebec, P. Tomše, A. Studen, M. Grmek, C. Tang, D. Eidelberg, M. Trošt (Ljubljana, Slovenia)

    Objective: To identify characteristic metabolic brain patterns specific for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) in a new cohort of patients and…
  • 2019 International Congress

    18F-DPA714 PET reveals neuroinflammatory activity in the Substantia nigra of patients with Parkinson disease

    S. Lavisse, C. Wimberley, S. Goutal, M. Bottlaender, B. Kuhnast, MA. Peyronneau, M. Sarazin, P. Hantraye, C. Thiriez, P. Remy (Fontenay Aux Roses, France)

    Objective: We investigated whether 18F-DPA714 imaging could be a sensitive marker of neuroinflammation in Parkinson disease (PD). We took into account the polymorphism of TSPO…
  • 2019 International Congress

    Amyloid load and cognitive decline in Parkinson’s disease: preliminary longitudinal findings

    M. Stark, T. Melzer, D. Myall, R. Keenan, T. Pitcher, KL. Horne, L. Livingston, M. Macaskill, J. Dalrymple-Alford, T. Anderson (Christchurch, New Zealand)

    Objective: To test for any association between amyloid deposition and future cognition in Parkinson’s disease, in a sample enriched for mild cognitive impairment. Background: Progressive…
  • 2018 International Congress

    [18F]FP-CIT and [18F]FDG PET findings in MSA patients with cognitive impairment

    KB. Lee, YJ. Park, C. Lee (Seoul, Republic of Korea)

    Objective: We investigated the brain dopaminergic system and glucose metabolism in multiple system atrophy (MSA) patients with cognitive impairment. Background: Since the first report of…
  • 2018 International Congress

    Study on feasibility to develop a central nervous system (CNS) Leucine-rich repeat kinase 2 (LRRK2) PET tracer

    Z. Zeng, P. Miller, T. Graham, L. Tong, D. Hesk, W. Li, E. Hostetler (West Point, PA, USA)

    Objective: To assess feasibility of developing a CNS LRRK2 PET tracer. Background: LRRK2 enzyme belongs to the leucine-rich repeat kinase family. Pathogenic mutations in the…
  • 2018 International Congress

    18F-FDG PET brain in Parkinsonism

    F. Amod (Durban, South Africa)

    Objective: To determine if 18F-FDG PET can differentiate Parkinson's Disease from Parkinson's-Plus syndromes Background: Parkinsonism is a clinical syndrome of tremor, rigidity, bradykinesia and postural…
  • 2018 International Congress

    Alterations of cortical metabotropic glutamate receptor-mediated signaling in patients with Parkinson’s disease

    JY. Lee, YK. Kim, SA. Shin, SH. Seo, JS. Lee, YS. Lee, JM. Jeong, B. Jeon (Seoul, Republic of Korea)

    Objective: To evaluate expression of brain metabotropic glutamatergic receptor 5 and the relationship with clinical measures in Parkinson’s disease patients. Background: Metabotropic glutamate receptor 5…
  • 2018 International Congress

    Amyloid deposition affects cognitive manifestations in Parkinson’s disease: The PPMI dataset

    E. Fiorenzato, R. Biundo, D. Cecchin, AC. Frigo, L. Weis, J. Kim, A. Strafella, A. Antonini (Venice, Italy)

    Objective: To investigate the contribution of amyloid depositions to cognitive deficits in the early phase of Parkinson’s disease (PD). Background: Involvement of amyloid deposits is…
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