Classify Parkinson’s Disease with Mild Cognitive Impairment: Machine Learning Approach
Objective: To determine how multimodal neuroimaging data can contribute to the classification of Parkinson’s disease (PD) patients with mild cognitive impairment (MCI) from PD without…Progression of dopaminergic and serotonergic dysfunction related to motor and nonmotor manifestations in apathetic and non-apathetic parkinsonian patients: a 4-year longitudinal double-tracer PET study
Objective: To investigate the progression of dopaminergic and serotonergic dysfunction and their relation to motor and nonmotor impairment in parkinsonian patients with or without apathy,…Study of cardiac sympathetic denervation by 18F-FDOPA PET-CT Imaging in early Parkinson disease (EPD) and Atypical parkinsonian syndromes (APS)
Objective: To evaluate utility of l-3,4-dihydroxy-6-[18F] fluoro-phenylalanine (18F-FDOPA) PET-CT imaging for cardiac sympathetic denervation in conjunction with nigrostriatal imaging in patients with early Parkinson disease (EPD) and Atypical…Relative Preservation of Serotonergic Function Increases Response to Treatment in Early PD
Objective: To investigate interactions between the serotonergic and dopaminergic systems in early PD as related to (i) response to treatment and (ii) dopamine (DA) release,…Correlating subcortical structure and function in idiopathic Parkinson’s disease: A cross-sectional morphometric and [18F]-DOPA PET study
Objective: To investigate whether the local geometric changes in the subcortical structures of patients with idiopathic Parkinson’s disease correlate with dopaminergic terminal functional integrity within…[11 C] DASB PET imaging in dopa-responsive dystonia patients: The role of serotonin in motor and non-motor symptoms
Objective: To assess the non-displaceable binding potential (BPND) of the serotonin transporter (SERT) in dopa-responsive dystonia (DRD) patients and to determine if an altered BPND…Functional connectivity changes in relation to dopaminergic decline in Parkinson’s over time: A resting-state fMRI and 11C-PE2I PET imaging study
Objective: To evaluate the functional connectivity patterns of basal ganglia subdivisions in relation to dopamine transporter density and motor features in patients with PD at…Neuronal correlates of oculomotor alterations in Huntington’s disease. A 18-FDG PET study
Objective: To explore the neuroanatomical correlates of the oculomotor abnormalities in Huntington's disease (HD) through a 18-FDG PET study Background: Alterations of the oculomotor function…Behavior and PET Imaging Study in Parkinsonian Rat Models Induced by Injection of 6-OHDA in Medial Forebrain Bundle
Objective: To employ behavioral test, positron emission tomography (PET) imaging and immunohistochemical staining to assess the changes of brain function and dopaminergic system in rat…A Study on Combined Brain Positron Emission Tomography (PET) – Magnetic Resonance Imaging (MRI) Using Fluorodeoxyglucose (18FDG) (FDG-PET/MRI) in Premanifest Huntington’s Disease Gene-expansion Carriers
Objective: By a combined brain PET–MRI using FDG, we wished to simultaneously characterize the structural and metabolic brain changes in premanifest HD gene-expansion carriers. Background:…
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