Cerebral Glucose Metabolic Features of GBA-Parkinson’s Disease as a window into cognitive impairment
Objective: to investigate cerebral glucose metabolism via fluorodeoxyglucose positron emission tomography (FDG-PET) and its correlation to clinical features in Parkinson’s disease (PD) patients with GBA1…Topographical heterogeneity of cholinergic system status in Multiple System Atrophy: A series report
Objective: To characterize individual-level topographical patterns of cholinergic upregulation and downregulation in Multiple System Atrophy (MSA) using a whole brain voxel-wise approach. Background: MSA is…Uncovering the heterogeneity of spatiotemporal trajectories of neurodegeneration in Parkinson’s disease: an early-phase 18F-FP-CIT PET study
Objective: To define the subtypes of Parkinson’s disease (PD) based on the spatiotemporal progression patterns of cerebral hypoperfusion. Background: Early-phase 18F-FP-CIT PET images, which are…Metabolic Patterns in Multiple System Atrophy: Brain Network Insights from Spatial ICA of FDG-PET
Objective: This study employs spatial independent component analysis (ICA) on 18F-fluorodeoxyglucose (FDG)-PET imaging to decompose metabolic heterogeneity in Multiple system atrophy (MSA), identifying key brain…Understanding the relationship between synaptic density and dopamine transporter availability in Parkinson’s disease
Objective: To evaluate how disease duration in PD affects the coupling of DAT (18F-FE-PE2I) and SV2A density (11C-UCB-J) in the nigrostriatal regions (where both tracers…Bistriatal hypermetabolism on 18-FDG PET-CT in tardive dyskinesia
Objective: Tardive dyskinesia (TD) describes various movement disorders developing after treatment with dopamine receptor blocking agents (DRBA), including stereotypy, akathisia, dystonia, tremor, tics and chorea.…[18F]PR04.MZ PET CT as a clinical tool in the differential diagnosis of PD and other atypical parkinsonian syndromes in the first 5 years of symptoms
Objective: Investigate if the [18F]PR04.MZ PET CT is a useful tool in the differential diagnosis of PD and atypical parkinsonian syndromes (AP), mainly MSA and…A Visual Interpretation Algorithm for Assessing 18F-Florzolotau PET Scans in Progressive Supranuclear Palsy
Objective: This study aimed to develop a visual reading algorithm dedicated to the evaluation of 18F-Florzolotau positron emission tomography (PET) scans in PSP. Background: The…Dopaminergic denervation and focal motor progression in early Parkinson’s Disease: A 5-year longitudinal study
Objective: To evaluate the progression of posterior putamen dopaminergic denervation in relation to motor progression in the less affected and more affected side of the…Key neural tracts involved in tau depositions and neurodegeneration as revealed by multimodal MRI and PET assays in progressive supranuclear palsy
Objective: Our study aimed to elucidate the impact of tau depositions on brain microstructure and macrostructure in progressive supranuclear palsy (PSP). Background: The link between…
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