Does smoking impact dopamine neuronal loss in de novo Parkinson’s disease?
Objective: To investigate whether smoking impacts striatal dopamine neuronal degeneration in Parkinson’s disease (PD), we compared striatal subregional dopamine transporter (DAT) binding between current-smokers and…Evaluation of SV2A expression with [18F]MNI-944 PET imaging in healthy controls (HC) and Parkinson disease (PD)
Objective: To evaluate [18F]MNI-944, a highly selective synaptic SV2A PET imaging tracer, as a biomarker for longitudinal studies in early PD. Background: PD symptoms manifest…[11C]PK11195 PET Imaging Reveals Neuroinflammation in Dementia with Lewy Bodies: NIMROD Study
Objective: To determine if subjects with dementia with Lewy bodies(DLB) have increased microglial activation in vivo compared to matched healthy controls as assessed using PET…Metabolic changes following transcranial magnetic resonance-guided focused ultrasound subthalamotomy
Objective: As part of a pioneer trial to investigate the use of transcranial magnetic resonance-guided focused ultrasound subthalamotomy (MRgFUS-STN) in Parkinson's disease (PD), this study addresses…Correlation analysis between dopamine release in striatal sub-regions and motor impairment in Parkinson’s disease subjects
Objective: To investigate correlations between the sub-regional dopamine release (DR) in the striatum of Parkinson’s disease (PD) subjects and sub-components of motor performance evaluated according…FDG PET studies in the differential diagnose of atypical parkinsonism and dementia syndromes.
Objective: To describe the fluorodeoxyglucose (FDG) metabolic pattern and clinical features in patients with clinical diagnose of atypical parkinsonism such as Progressive Supranuclear Palsy (PSP),…The Relative Preservation of the Dopaminergic Neuroal Loss of Patients with Parkinson’s Disease Having Dopamine-Unresponsive Resting Tremor
Objective: To investigate the difference of dopaminergic neuronal loss between PD patients with dopamine-unresponsive and -responsive resting tremor. Background: Resting tremor (RT) is one of…18F-labeled FP-CIT PET Findings in a series of cirrhotic patients with parkinsonism
Objective: Our object is to evaluate the cirrhotic patients with parkinsonism using the presynaptic dopamine transporter (DAT) positron emission tomography (PET) imaging for dopaminergic deficit.…Specific Metabolic Brain Networks Associated with Parkinsonian and Cerebellar Variants of Multiple System Atrophy
Objective: To identify specific metabolic brain networks for parkinsonian (MSA-P) and cerebellar (MSA-C) variants of MSA. Background: MSA is associated with a disease-related metabolic brain network (MSARP)…Link between striatal dopamine uptake and cortical dysconnectivity in Parkinson’s disease
Objective: This study aims to explore pathways of reduced striatal dopamine synthesis in PD that may affect striato-cortical connectivity and implicate in altered glucose metabolism…
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