Key neural tracts involved in tau depositions and neurodegeneration as revealed by multimodal MRI and PET assays in progressive supranuclear palsy
Objective: Our study aimed to elucidate the impact of tau depositions on brain microstructure and macrostructure in progressive supranuclear palsy (PSP). Background: The link between…18F-Florzolotau Positron Emission Tomography Imaging Correlates with Regional Brain Atrophy and Plasma Biomarkers in Tauopathy Parkinsonism Syndrome
Objective: We aim to investigate the relationship between regional 18F-florzolotau uptake and clinical severity, structural volume changes, and plasma markers in tauopathy parkinsonism syndrome. Background:…Remote Digital Longitudinal Assessment of Speech, Fluency and Cognitive Function in Progressive Supranuclear Palsy
Objective: To conduct a comparative analysis of remote digital assessment methods for evaluating speech, fluency, and cognitive function in individuals diagnosed with Progressive Supranuclear Palsy…Clinical features and brain [18F] FDG PET patterns in patients with progressive supranuclear palsy with and without ventricular dilatation
Objective: To describe the clinical features and the metabolic patterns assessed by the brain [18F] FDG-PET in a cohort of PSP patients with or without…Peripheral immune profile and neutrophil-to-lymphocyte ratio in Progressive Supranuclear Palsy
Objective: This study aimed to evaluate the peripheral immune profile in patients with Progressive Supranuclear Palsy (PSP) compared with patients with Parkinson’s disease (PD) and…Hydrocephalic Progressive Supranuclear Palsy: An Underrecognized Entity
Objective: We describe a case of NPH-like presentation of PSP, review literature surrounding this entity, and discuss key diagnostic considerations and implications. Background: Despite advances…Differentiating Progressive Supranuclear Palsy from Corticobasal Syndrome Using Cortical Diffusion MRI
Objective: To compare cortical microstructural measures in Progressive Supranuclear Palsy (PSP) and Corticobasal Syndrome (CBS) using cortical diffusion magnetic resonance imaging (MRI). Background: Differential diagnosis…The value of volume of the subthalamic nucleus in diagnosis of progressive supranuclear palsy
Objective: To investigate the diagnostic accuracy of STN volume in PSP using quantitative susceptibility mapping (QSM) imaging and 3T MRI. Background: Various MRI markers are…Cell-specific MAPT gene expression is preserved in tau cytopathologies in Progressive Supranuclear Palsy
Objective: To systematically map and quantify MAPT expression in neurons, astrocytes and oligodendroglia across different brain regions to determine whether cell type and/or regional differences…Impulse control disorder related to dopaminergic therapy in progressive supranuclear palsy
Objective: To report a patient with progressive supranuclear palsy (PSP) in whom an impulse control disorder (ICD) was triggered by a dopaminergic therapy. Background: ICDs…
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