Gait and Balance Characteristics in Atypical Parkinsonian Syndromes
Objective: To characterize a cohort of patients with multiple system atrophy (MSA) and progressive supranuclear gaze palsy compared to idiopathic Parkinson’s disease (IPD) patients according…Retinal thickness as a marker of disease progression in progressive supranuclear palsy
Objective: We measured changes of retinal thickness, and compare them with clinical features and intracranial neurodegeneration in progressive supranuclear palsy (PSP) cohort. Background: PSP has a…A trail towards understanding cognitive impairment in PSP
Objective: To investigate cognitive impairment in 22 patients with Progressive Supranuclear Palsy with Richardson syndrome (PSP-RS). Background: PSP is a neurodegenerative disease and common differential…APOE effect on Progressive Supranuclear Palsy phenotypes
Objective: To assess the influence of the Apolipoprotein E (APOE) gene variants on Progressive supranuclear palsy (PSP) phenotypic expression. Background: PSP is a rare neurodegenerative…Imaging Tau in Atypical Parkinsonisms: Meta-Analysis of in vivo PET Imaging Findings
Objective: To determine the most accurate and reliable tau PET tracers for providing differential diagnosis of PSP and CBD from PD. Background: Parkinsonism is classified…The Magnetic Resonance Parkinsonism Index as a diagnostic marker for differentiating PSP from IPD
Objective: The Magnetic Resonance Parkinsonism Index (MRPI) has been proposed as an enhancement of the Midbrain to Pons Ratio (MTPR) as a diagnostic tool for…COMBINED CSF α-SYN RT-QuIC, CSF NFL AND MIDBRAIN-PONS PLANIMETRY IN DEGENERATIVE PARKINSONISMS: FROM BEDSIDE TO BENCH, AND BACK AGAIN
Objective: (1) to assess the combined diagnostic ability of CSF NFL, CSF RT-QuIC α-SYN and midbrain/pons MRI measures in degenerative parkinsonisms; (2) to interpret results…Cognitive and Psychiatric Correlates of Fear of Falling in Progressive Supranuclear Palsy and Multiple System Atrophy
Objective: To evaluate the clinical correlates of fear of falling (FoF) in patients with Progressive Supranuclear Palsy (PSP) and Multiple System Atrophy (MSA) Background: FoF…Probable Four-repeat tauopathy criteria in Corticobasal Syndrome: diagnostic accuracy, clinical features and imaging biomarkers
Objective: To compare the “probable four-repeat (4R)-tauopathy” criteria[1] with the clinical research(cr) criteria for corticobasal degeneration (CBD) [2] regarding diagnostic accuracy to predict a negative…Effects of venlafaxine on neuropsychiatric and motor symptoms in patients with progressive supranuclear palsy
Objective: This prospective, ongoing, interventional trial is related to the ProPSP registry and aims to characterize the effects of venlafaxine, a serotonin-norepinephrine reuptake inhibitor, on…
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