Expanding the NINDS Parkinson’s Disease Biomarkers Program – Utilizing a Major Biomarker Resource to Address Atypical Parkinsonisms and Related Conditions
Objective: Expansion of a carefully curated resource for clinical and biosample data to address a critical need for biomarker discovery in Atypical Parkinsonisms and related…Open-label extension (OLE) of a multiple ascending dose (MAD) study of BIIB092 in participants with PSP: Safety analysis
Objective: To assess safety of BIIB092 in participants with progressive supranuclear palsy (PSP) in an OLE of a MAD study. Background: BIIB092 is a humanized…A longitudinal study of brain quantitative MRI analysis before and after diagnosis of progressive supranuclear palsy
Objective: We analyzed longitudinal change in MRI imaging in PSP from the period before clinical diagnosis. Six patients with clinically diagnosed PSP including 1 case…Comparative study of the cognitive and behavioral disturbances between progressive supranuclear palsy phenotypes
Objective: Explore cognitive and behavioural disturbances between subtypes of progressive supranuclear palsy (PSP). Background: Although clinical diagnosis of PSP is based on specific motor symptoms,…Striatal dopamine function in multiple system atrophy and progressive supranuclear palsy: A meta-analysis of imaging studies
Objective: To investigate differences in striatal presynaptic dopamine function between multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) using combined data from all available…The characteristic of gait in progressive progressive supranuclear palsy
Objective: To elucidate the characteristic of gait in patients with progressive supranuclear palsy (PSP) and compare to healthy elderly and patients with Parkinson’s disease (PD)…Affective impairment and emotional tone of early Richardson’s syndrome and Progressive Supranuclear Palsy with predominant parkinsonism: The role of Alexithymia and Anhedonia
Objective: To define qualitative and quantitative differences of alexithymia and anhedonia among Progressive Supranuclear Palsy (PSP) with predominant parkinsonism (PSP-P), Richardson’s syndrome (PSP-RS) and Parkinson’s…Superior cerebellar peduncles atrophy of PSP on PADRE imaging; comparison with idiopathic PD
Objective: The purpose of our study was to determine whether atrophy of Superior cerebellar peduncles (SCP) on phase-weighted magnetic resonance imaging technique (PADRE) was useful…Oculomotor Behavior in Healthy Caribbean: Does it reflect an increased vulnerability to degenerative Parkinsonism?
Objective: To investigate the impact of environmental factors on eye movement performances in two populations composed of carefully selected healthy subjects with strikingly different ethnic…Immunological causes of atypical parkinsonism
Objective: To study the clinical and biochemical features of atypical parkinsonism. Evaluate results of the immune-mediated treatment Background: Atypical parkinsonism is a heterogeneous group of…
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