Unraveling the Genetic Architecture of Progressive Supranuclear Palsy in East Asians
Objective: We aim to elucidate the genetic architecture of progressive supranuclear palsy (PSP) in East Asians through whole-exome sequencing in a multi-center study in Taiwan.…Parkinsonism in Uzbekistan: Clinical and Demographic Insights from 2024
Objective: We retrospectively analyzed the medical records of all parkinsonism patients admitted to our clinic in 2024, examining neurological, psychiatric, radiological, and demographic characteristics of…Gait Variability is Associated with Executive Function in Progressive Supranuclear Palsy
Objective: This study aims to investigate the relationship between executive function and gait in PSP using clinical assessments and objective gait analysis with wearable sensors.…Identification of Genetic Variants in Progressive Supranuclear Palsy in China
Objective: To delineate the genetic landscape of progressive supranuclear palsy (PSP) in Chinese patients.Progressive supranuclear palsy is a neurodegenerative disorder primarily considered sporadic, with MAPT…Changes in Inhibitory Control Differentiate Progressive Supranuclear Palsy from Early Parkinson’s Disease
Objective: To describe distinct type of errors and frequency of perseverative errors in executive, memory, language, and attentional tasks in PSP and PD. Background: Progressive…The Sedentary Index (SI) for Daily Life Activity Monitoring in Progressive Supranuclear Palsy (PSP)
Objective: To confirm the feasibility of daily life physical activity monitoring in PSP using a single activPAL sensor, and to examine preliminary associations between overall…Clinical Features Suggestive of Alpha-Synucleinopathy in Progressive Supranuclear Palsy
Objective: To compare the presence of symptoms suggestive of synucleinopathy between PSP-parkinsonism (PSP-P), Parkinson's disease (PD) and PSP-Richardson syndrome (PSP-RS). Background: Clinical signs with high…A Case of Mixed Presentation of 4R Tauopathies
Objective: To describe the diagnostic challenges, and management of a patient with overlapping features of corticobasal syndrome (CBS) and progressive supranuclear palsy (PSP) Background: CBS…Plasma tau-species-containing neuron-derived extracellular vesicles as potential biomarkers for progressive supranuclear palsy
Objective: This study aimed to develop and validate novel plasma PSP biomarkers based on tau-species-containing neuron-derived extracellular vesicles (NDEVs) in two independent cohorts (discovery and…Clinical Deficits, Quality of Life and Caregiver Burden across PSP Phenotypes
Objective: To assess clinical deficits, quality of life and caregiver burden across progressive supranuclear palsy (PSP) phenotypes considering also other variables such as age, sex…
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