Atypical Parkinsonian Syndrome with evocative brain MRI imaging. About seven cases.
Objective: The diagnosis of Parkinson's disease and parkinsonian syndromes remains clinically difficult, is based on clinical diagnostic criteria, MRI plays a major role in the…Neuroimaging analysis of postural instability in Progressive Supranuclear Palsy: a Voxel‐based morphometry approach
Objective: The aim of the study was to identify the mainly brain regions involved in postural instability (PI) in Progressive Supranuclear Palsy (PSP) with a…White matter integrity in patients with PSP-RS and VaP: A TBSS Study
Objective: The purpose of the present study was to compare alterations of brain white-matter microstructure and tissue integrity in PSP-RS and VaP patients using Diffusion…A tau-directed monoclonal antibody could alter the tau pathology of progressive supranuclear palsy
Objective: The purpose of this study is to examine the modification of tau pathology in brain regions of a patient with progressive supranuclear palsy (PSP)…Introducing the molecular subtyping of Progressive Supranuclear Palsy: a proof of concept
Objective: To enhance understanding of the molecular mechanisms underlying disease heterogeneity in Progressive supranuclear palsy (PSP) Background: PSP is a 4R-tauopathy characterised by subcortical pathology…In vivo proteomic investigation of deeply phenotyped parkinsonian syndromes for biomarkers of differential diagnosis
Objective: To investigate deeply-phenotyped cohorts of parkinsonian syndromes using proteomic technologies for identification of biomarkers for differential diagnosis Background: Proteomic technologies like Olink® Explore 3072…Prognostic impact of frontal-lobe clinical bedside signs in progressive supranuclear palsy
Objective: To identify clinical bedside examination signs indicative of frontal lobe dysfunction with a prognostic value in patients with progressive supranuclear palsy (PSP). Background: The…Atypical progression of motor symptoms in Facio-Scapulo-Humeral Dystrophy: clinical worsening or overlap?
Objective: This case highlights the importance of considering possible overlaps with PSP and other neurodegenerative diseases. Background: Facio-Scapulo-Humeral Dystrophy is a common muscular dystrophy featuring…18f-PI-2620 tau PET neuroimaging, tau protein burden and 18f-PI-2620 tau autoradiography on human postmortem brain tissue in a PSP patient
Objective: Our aim is to describe the findings of 18F-PI-2620 tau-PET imaging, together with tau protein burden and 18F-PI-2620 tau autoradiography in brain tissue from…Early cortical atrophy is related to depression in Parkinson’s disease
Objective: To investigate depression in relation to medial temporal lobe atrophy (MTA), global cortical atrophy (GCA) and white matter hyperintensities (WMH) in neuropathologically confirmed patients…
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