Use of pimavanserin in patients with Parkinson’s disease psychosis: Subgroup analysis of efficacy and safety in patients with and without cognitive impairment
Objective: A planned subgroup analysis of a phase 3 study was performed to evaluate the efficacy and safety of pimavanserin (PIM) in Parkinson’s disease psychosis…A Phase 2 Study of Nelotanserin, a Novel 5HT2A Receptor Inverse Agonist, in Dementia with Lewy Bodies and Parkinson’s Disease Dementia Subjects Experiencing Visual Hallucinations
Objective: To evaluate the safety and efficacy of nelotanserin in Lewy body dementia subjects experiencing visual hallucinations. Background: Nelotanserin is a selective 5HT2A receptor inverse…Key clinical milestones 15 years and onwards after DBS-STN surgery – a retrospective analysis of patients that underwent surgery between 1993 and 2001
Objective: In this paper we investigated patients with advanced Parkinson's disease (PD) operated at our center with subthalamic nucleus deep brain stimulation (STN-DBS) for at…Aberrant resting state functional brain networks in patients with Parkinson’s disease and visual hallucinations
Objective: To explore the neural correlates of Visual Hallucinations (VH) in patients with Parkinson’s disease (PD). Background: Psychosis is one of the commonly observed non-motor…Postoperative delirium after deep brain stimulation surgery for Parkinson’s disease
Objective: To investigate the potential predictive factors of postoperative delirium after deep brain stimulation surgery for Parkinson’s disease (PD). Background: Subthalamic nucleus deep brain stimulation…Predictors for psychosis in Huntington’s disease: preliminary analysis of the Enroll-HD database.
Objective: To evaluate predictors for psychosis in HD. Background: Behavioral problems are present across all stages of HD, even preceding the development of the motor…Parkinson Syndrome associated with inositol-1,4,5-triphosphate receptor antigen type 1 (ITPR1) antibodies
Objective: To illustrate an unusual clinical presentation of Parkinson´s disease (PD) that was effectively treated with immune adsorption. Background: Autoimmune mediated movement disorders may be…Chorea and psychosis as stroke presentation : report and brief review
Objective: Describe phenomenology of rare movement disorders in stroke presentation and it pathophysiology Background: Acute movement disorders are a rare presentation of ischaemic stroke. hemichorea…Late-Onset Wilson’s disease, Dementia, Ekbom syndrome and whitte matter hyperintensities
Objective: The aim of this study is to describe a patient with late-onset Wilson’s disease, dementia and Ekbom Syndrome. Background: Wilson's disease is an autosomal-recessive disorder…The clinically-available anti-depressant mirtazapine alleviates both psychosis and dyskinesia in the MPTP-lesioned marmoset
Objective: To determine the effect of mirtazapine, a clinically-available anti-depressant, on psychosis and dyskinesia in Parkinson’s disease (PD). Background: Psychosis and dyskinesia cause significant morbidity…
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