Neuroimaging Extra-Striatal D2 Receptors in Parkinson’s Disease with Rapid Eye Movement Sleep Behaviour Disorder
Objective: Our aim was to characterize the extra-striatal dopamine in Parkinson’s disease (PD) with and without rapid eye movement sleep behaviour disorder (RBD) using in…Autonomic symptoms as biomarkers in REM Sleep Behavior Disorder and Parkinson’s disease
Objective: This study was designed to evaluate autonomic functions in iRBD compared to PD and controls including longitudinal follow-up assessments to evaluate their potential to…RBD and autonomic dysfunction in newly diagnosed Parkinson’s disease patients
Objective: To determine whether newly diagnosed Parkinson’s disease (PD) patients with REM sleep behavior disorder (RBD) are more likely to have symptoms of autonomic dysfunction.…Intestinal transit in early-moderate Parkinson’s disease correlates with probable RBD – subclinical esophageal dysmotility does not correlate
Objective: To investigate esophageal and intestinal transit times in early-moderate Parkinson's disease (PD) and to study correlations with probable RBD and subjective symptoms. Background: Intraneuronal…The clinical features of non-motor symptoms in Parkinson’s Disease with Rapid Eye Movement Sleep Behavior Disorder(RBD)
Objective: To review non-motor symptoms of PD with RBD, To explore the effects of RBD on PD. Background: Non-motor symptoms of PD with RBD were…Spreading ɑ-synuclein pathology initiated from the sublaterodorsal tegmental nucleus models RBD followed by Parkinsonian phenotypes in mice
Objective: To recapitulate ɑ-synucleinopathy based RBD-like behaviors in mice which could further proceed to develop Parkinsonian behavioral and histopathological phenotypes. Background: Idiopathic REM sleep behavior…Parkinson Progression Marker Initiative 2.0 – New Science/New Cohorts
Objective: The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes,…Relationship between REM sleep without atonia and sleep architecture in multiple system atrophy
Objective: To investigate whether REM sleep without atonia (RWA) is associated with sleep architecture in patients with multiple system atrophy (MSA). Background: In MSA patients,…Improving estimation of Parkinson’s disease risk – enhancing the PREDICT-PD algorithm
Objective: To develop and test an enhanced algorithm for the prediction of Parkinson’s disease (PD) risk. Background: The PREDICT-PD algorithm estimates risk of PD using…Development and validation of a profile of peripheral immune biomarkers for Parkinson’s disease: A multicenter, retrospective study
Objective: This multicenter study was designed to investigate the association between multiple peripheral immune biomarkers and the risk of Parkinson’s disease (PD). Background: Several studies…
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