Intestinal transit in early-moderate Parkinson’s disease correlates with probable RBD – subclinical esophageal dysmotility does not correlate
Objective: To investigate esophageal and intestinal transit times in early-moderate Parkinson's disease (PD) and to study correlations with probable RBD and subjective symptoms. Background: Intraneuronal…The clinical features of non-motor symptoms in Parkinson’s Disease with Rapid Eye Movement Sleep Behavior Disorder(RBD)
Objective: To review non-motor symptoms of PD with RBD, To explore the effects of RBD on PD. Background: Non-motor symptoms of PD with RBD were…Spreading ɑ-synuclein pathology initiated from the sublaterodorsal tegmental nucleus models RBD followed by Parkinsonian phenotypes in mice
Objective: To recapitulate ɑ-synucleinopathy based RBD-like behaviors in mice which could further proceed to develop Parkinsonian behavioral and histopathological phenotypes. Background: Idiopathic REM sleep behavior…Parkinson Progression Marker Initiative 2.0 – New Science/New Cohorts
Objective: The Parkinson Progression Marker Initiative 2.0 (PPMI 2.0) is a longitudinal, observational, multi-center natural history study to assess progression of clinical features, digital outcomes,…“Brain-first” vs. “body-first” Parkinson’s disease is determined by RBD-status – a multi-modality imaging study
Objective: In a multi-modality imaging study, we test the hypothesis that Parkinson’s disease (PD) can be divided into two strikingly distinct phenotypes: (1) PD patients,…Efficacy and Safety of the 5-Hydroxytryptophan on REM Sleep Behavior Disorder in Parkinson’s Disease.
Objective: To evaluate the efficacy of the 5-HTP on RBD status in patients with Parkinson's disease (PD). Background: REM sleep behavior disorder (RBD) is reported…Potential treatment considerations for refractory REM behavior disorder
Objective: A meta-analysis of alternative treatment therapies for refractory REM behavior disorder. Background: Parkinson’s disease is a neurodegenerative syndrome that affects motor and non-motor functions.…Sleep Aspects on Video-Polysomnography in P.A53T SNCA Mutation Carriers
Objective: To determine whether REM sleep behavior disorder (RBD) and other sleep abnormalities occur in carriers of the p.A53T alpha-synuclein gene (SNCA) mutation, the prototypical…In the shadow of Parkinson disease: what to tell patients with REM sleep behavior disorder?
Objective: To describe challenges to patient counseling in REM sleep behavior disorder (RBD). Background: RBD is a significant risk factor for development of Parkinson disease…The influence of gender, associated neurological disorder and motive for polysomnography (PSG) in the manifestations of REM sleep behaviour disorder (RBD)
Objective: To access the interrelation and relative influence of gender, associated neurological disorder and context of referral to PSG on the manifestations of (RBD). Background:…
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