Affected tongue movements in idiopathic REM sleep behavior disorder
Objective: In Parkinson’s disease (PD), recognition of speech deviations often follows clinical diagnosis. But what if speech is a prodromal biomarker in PD? The study…Sleep stability, arousals and cycle structure in alfa-synucleinopathies: a comparative study between isolated REM sleep behaviour disorder (iRBD), Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB)
Objective: To compare sleep stability, arousals and sleep cycle structure between two sets of diagnosis: iRBD vs PD vs DLB; patients with RBD (RBD+) vs…Feasibility of artificial intelligence in predicting early phenotype conversion of REM Sleep Behavior Disorder
Objective: The goal of this study was to investigate the feasibility of deep learning in the prediction of disease conversion in RBD patients. Background: Rapid…Design of a prodromal screening study for subtypes in Parkinson’s Disease
Objective: To follow-up prodromal Parkinson’s Disease (PD) subtypes in a longitudinal cohort study, validating new biomarkers and ethical guidelines for early detection of PD. Background:…Relationship between brain bioelectrical activity during REM/NREM sleep, grey matter changes and visual disorders in patients with RBD in Parkinson’s disease
Objective: To investigate the brain bioelectric activity during REM/NREM sleep and determine the relationship with visual impairment and structural brain alteration in non-demented PD patients…Multimodal MRI assessment of the substantia nigra in premotor and motor stages of parkinsonism
Objective: To investigate substantia nigra (SN) MRI abnormalities through Neuromelanin (NM) and diffusion MRI (dMRI) with Neurite Orientation Dispersion and Density Index (NODDI) in the…Screening of REM Sleep Behavior Disorder and the relation with parkinsonism symptoms in the elderly in southern Brazil: a preliminary population-based study
Objective: To describe the preliminary screening profile for suspected REM sleep behavior disorders (RBD) and association with parkinsonian symptoms in the elderly in a population-based…Autonomic Nervous System Dysfunction in idiopathic REM sleep behaviour disorder
Objective: To characterise autonomic impairment in REM sleep behaviour disorders, and to investigate the pathophysiological link between autonomic impairment and REM sleep behaviour disorder Background:…Striatal Subregion Analysis Associated with REM Sleep Behavior Disorder in Parkinson’s disease
Objective: Herein we evaluated the regional selectivity of presynaptic striatal dopaminergic denervation associated with RBD in drug-naive early PD. Background: REM sleep behavior disorder (RBD)…Marker Progression and Sample Sizes Estimates for Trials in Prodromal Parkinson’s Disease: A Multicenter Study
Objective: To inform the design of randomized neuroprotective trials in prodromal Parkinson’s disease (PD) by assessing the progression of prodromal markers in idiopathic rapid eye…
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