Metabolic patterns and neurodegeneration in isolated REM sleep behavior disorder
Objective: To elucidate the role of Parkinson’s disease (PD)-related brain metabolic patterns as a biomarker in isolated rapid-eye-movement sleep behavior disorder (iRBD) for clinical correlation…Altered metabolic and functional resting state activity in cognitively unimpaired and impaired Parkinson’s disease patients
Objective: To assess the correspondence between functional connectivity and metabolic covariance in healthy controls and Parkinson’s disease patients (PD) with and without cognitive impairment. Background:…Abnormal Cerebral Glucose Metabolism and Dopaminergic Dysfunction in Patients with Parkinson’s Disease with Bilateral Onset
Objective: To explore the characteristics of the abnormal cerebral glucose metabolism and dopamine distribution in patients with Parkinson's disease (PD) with bilateral onset. Background: PD is…Central Insulin Resistance Index is Independent of Peripheral Insulin Resistance in Parkinson’s disease
Objective: To correlate brain insulin signalling with peripheral insulin resistance using neuronally derived blood exosomes in patients with Parkinson's Disease (PD) Background: Insulin signaling abnormalities may…Imaging Brain Insulin Resistance in Parkinson’s Disease using [¹⁸F]FDG-PET
Objective: To obtain a glucose brain uptake survey of Parkinson's Disease (PD) patients with or without insulin resistance (IR). Background: IR is common in PD…FDG-PET and metabolomics in PD-associated GBA variants
Objective: To assess the clinical, cognitive, metabolic, and imaging phenotypes of PD patients carrying the variants p.E365K and p.T408M in the GBA gene (NM_000157.3). Background:…Associations between Functional Networks and Temporal Discrimination Thresholds in Cervical Dystonia patients and their unaffected relatives
Objective: To investigate resting state functional networks across cervical dystonia patients and their unaffected relatives with and without abnormal temporal discrimination thresholds (TDTs) based on…Brain PET metabolic substrate of Impulse Control Disorders in Parkinson’s Disease
Objective: The aim of this study was to describe the cerebral metabolic PET substrate and related connectivity changes in Parkinson's disease patients with impulse control…Assessing Nigral Functional Connectivity in Parkinson’s Disease with Resting State Functional MRI
Objective: To evaluate functional connectivity of SN with basal ganglia and motor cortex in Parkinson’s disease (PD) using resting state functional MRI (RS fMRI). Background:…Freezing of gait in Parkinson’s disease: A stopping deficit?
Objective: We evaluated the role of inhibition in freezing of gait, and related performance on a behavioral stopping task to the structural integrity of the…