The Role of the PD Diary Trainer/Reviewer in Parkinson’s Disease Clinical Trials
Objective: To examine the experience profile of PD Diary raters in clinical trials Background: The Parkinson’s Disease (PD) Home Diary (Hauser, 2000)1 is a widely…Does MDS-UPDRS provide greater sensitivity to mild disease than UPDRS for assessing motor severity in early Parkinson’s disease?
Objective: To test whether The Movement Disorder Society revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part III (Motor Examination) items provide increased sensitivity…The Hauser Diary knowledge test as a tool to improve Rater Training Programs in Parkinson’s disease clinical trials
Objective: To identify the areas with specific training needs for Rater Training Programs (RTP) on the Hauser Diary in Parkinson’s disease (PD) clinical trials Background:…Validation of the Thai version of the MDS-UPDRS
Objective: To validate the Thai translation of the MDS-sponsored revision of the UPDRS (MDS-UPDRS). Background: The MDS-UPDRS was published in 2008 to assess different domains…Secondary endpoints of a randomized, placebo-Controlled Pilot Study to evaluate the safety of lyophilized PRIM-DJ2727 in Parkinson’s disease
Objective: To evaluate the impact of fecal microbiome transplant (FMT) on disease progression as a secondary outcome of a safety study using PRIM-DJ2727 in Parkinson's…The influence of culture on the relationship between subjective and objective assessments of dyskinesia severity.
Objective: To explore the relationship and rate of agreement between patient and clinician evaluation of dyskinesia severity and impact on function across multiple cultures. Background:…Novel approach to MDS-UPDRS monitoring in clinical trials: Longitudinal Item Response Theory Models
Objective: Using the unique advantages of Item Response Theory (IRT), we developed unidimensional and multidimensional models to investigate non-tremor and tremor MDS-UPDRS Part 3 changes…Reliability and Validity of the Greek Translation of the Scale for Assessment and Rating Ataxia in Ataxic Children
Objective: Translation and Cross-cultural adaptation of the Scale for Assessment and Rating Ataxia (SARA) in Greek ataxic pediatric population. Background: Ataxia in the pediatric population…Effects of levodopa on cognitive functions in Parkinson’s disease
Objective: To assess the dynamics of cognitive functions (CF) under the influence of levodopa in PD patients Background: Our research is devoted to an urgent problem-the…MDS Translation Program for MDS-UPDRS, UDysRS, and MDS-NMS
Objective: To summarize the status of the ongoing MDS-sponsored translation programs for non-English versions of the MDS-UPDRS, UDysRS, and MDS-NMS. Background: The MDS-UPDRS, UDysRS, and…
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