Lived Experiences in early clinical PD: Developing a Framework of a Novel Patient-reported Outcome (PRO) Fit-for-purpose for Disease Modification Therapeutic Trials
Objective: To characterize the lived experience of individuals at a prodromal stage of PD or with a recent clinical diagnosis. Background: There is no validated…Archimedes spiral based non-linear regression machine learning model for predicting tremor’s severity
Objective: To predict tremor severity using the Archimedes spiral drawing, a commonly used item in tremor assessment scales. Background: The Archimedes spiral is widely used…Eye movement abnormalities in GBA1-related Parkinson’s disease and non-manifesting GBA1-carriers
Objective: To perform an in-depth characterization of eye movement abnormalities in Parkinson’s disease (PD) and non-manifesting carriers of GBA1 pathogenic variants. Background: Eye movement abnormalities…Development of a Rating Instrument to Identify Catatonia by Virtual Viewing of Motor Assessments
Objective: To develop a rating instrument to identify catatonia by virtual viewing of motor assessments Background: Catatonia is a motor comorbidity complicating mental and physical…Can Wearable Inertial Sensors Accurately Reflect Parkinson’s Disease Severity? A Systematic Review and Meta-Analysis
Objective: To evaluate the ability of inertial measurement units (IMUs) in detecting the severity of motor symptoms in Parkinson’s disease (PD) by examining the relationship…Development of the Lewy Body Dementia Domain Rating Scale (LBD-DRS): A disease-specific outcome measure
Objective: To develop and refine the Lewy Body Dementia Domain Rating Scale (LBD-DRS) as a disease-specific outcome measure tailored to the unique clinical features of…Comparison of 3 Tests for Subjective Cognitive Complaints in Early Parkinson’s Disease
Objective: To compare 3 scales which have been used in literature to determine subjective cognitive complaints (SCC) in Parkinson’s disease (PD) and explore their relationship…Disease Monitoring through the PKAN Disease Rating Scale (PKAN-DRS) in Pantothenate Kinase-Associated Neurodegeneration (PKAN)
Objective: To assess the utility of PKAN-DRS as an outcome measure for monitoring disease progression in PKAN . Background: The PKAN-DRS assess multiple domains affected…Redefining the Finger-tapping Test in Parkinsonian Patients: Finger to Crease Instead of Finger-to-tip
Objective: To evaluate the competence of finger to crease (F-C) variation of the finger tapping test as opposed to the traditional method (F-T) in detecting…Implementation of the Distress Thermometer in a Movement Disorder Clinic
Objective: To present the findings from the implementation of widespread screening for psychosocial distress using a distress thermometer (DT) in a Movement Disorder clinic. Background:…
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