Motor compensation in Parkinson’s disease: a multimodal neuroimaging study
Objective: To study motor compensation mechanisms in Parkinson's disease. Background: Whereas akinesia in Parkinson's disease (PD) is linked to dopaminergic neurons death and striatal dopamine depletion,…No link between striatal dopaminergic axons and dopamine transporter imaging in Parkinson’s disease
Objective: The objective of this study was to investigate if dopamine transporter (DAT) binding is associated with dopaminergic neurites in the putamen. Background: Dopamine transporter…Correlation between cerebral perfusion and striatal dopamine transporter activity by dual SPECT study in Parkinsonian syndromes
Objective: We aimed to investigate the correlations between brain perfusion and striatal dopamine transporter (DAT) activity in parkinsonian syndromes and to characterize the difference in…Weight loss is associated with rapid striatal dopaminergic degeneration in Parkinson’s disease
Objective: To investigate whether weight loss has a longitudinal association with striatal dopaminergic degeneration in Parkinson's disease (PD). Background: Weight loss in PD is associated…Effect of exercise on neurodegenerative parkinsonism unmasked by dopamine blocking drugs (DRBD)
Objective: To test whether aerobic walking influences clinical status, biochemical and radiologic markers associated with degenerative parkinsonism unmasked by DRBD. Background: Failed trials of putative…No differences in the total burden of non-motor symptoms between Parkinson’s disease and non-degenerative parkinsonism
Objective: To compare the total burden of non-motor symptoms between Parkinson's disease and non-degenerative parkinsonism and to study the possible dopaminergic background of these symptoms.…The clinical value of SPECT in identifying dystonic muscles of patients with cervical dystonia
Objective: The aim of this study is to compare the efficacy of selecting target muscles for botulinum toxin injection by abnormal movement pattern and by…Apathy in rapid eye movement sleep behaviour disorder is associated with serotonin depletion in the raphe nuclei
Objective: To investigate whether apathy is related to serotonin depletion in the raphe nuclei in patients with rapid eye movement sleep behaviour disorder (RBD), a…Phenotypic Heterogeneity and Variability of Nigrostriatal Dopaminergic Function in a Dopa-Responsive Dystonia
Objective: To evaluate presynaptic nigrostriatal dopaminergic function in a Dopa-responsive dystonia (DRD) family with guanosine triphosphate cyclohydrolase 1 (GCH-1) mutation. Background: Mutation of GCH-1 located…Atypical Dopamine Responsive Parkinsonism in HIV Seroconversion
Objective: To add to the current body of knowledge of the association of HIV infection and dopamine responsive parkinsonism. Background: South Africa has one of…
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