Swimming against the current: Successful implementation of functional neurosurgery programs in underserved regions of Chile
Objective: To show the experience of implementing a functional neurosurgery program with Deep Brain Stimulation (DBS) for patients with Parkinson's Disease (PD), in low-income regions…GDNF Gene Therapy for Parkinson’s Disease (PD): Preliminary Safety and Clinical Findings from a Phase Ib Study
Objective: Assess the safety and tolerability of intraputaminal AAV2-GDNF in mild to moderate PD Background: Glial cell line-derived neurotrophic factor (GDNF) is critical for dopaminergic…Preliminary real-world surgical data collection in RAD-PD
Objective: To describe surgical practices in a cohort of patients with Parkinson’s disease (PD) undergoing deep brain stimulation (DBS). Background: DBS is well-established to improve…Prevention and management of Deep Brain Stimulation (DBS) surgical site infections (SSI) – multicentre survey of UK practice.
Objective: The aim of this survey was to better understand trends, patterns and practices of DBS surgical site care in the UK. Background: Deep brain…Knowledge and Attitudes among young Neurologists towards Surgery in Movement Disorders
Objective: To assess the knowledge and attitudes of young neurologists towards the surgical interventions in movement disorders. Background: Surgical management of patients with movement disorders…Evolving inclusion criteria in early manifest Huntington’s disease (HD) to address striatal atrophy: Lessons from HD-GeneTRX-1, the first gene therapy trial
Objective: To describe the early screening experience and evidence-based adaptations to the inclusion criteria for HD-GeneTRX-1 (NCT04120493). Background: AMT-130 is an AAV5-based gene therapy intended…Role of the Stereotactic Dentatotomy for the management of Movement Disorders
Objective: Evaluate the antecedents about the clinical outcomes of stereotactic dentatotomy in the management of diverse motor disorders. Background: The dentatotomy is a surgical technique…A retrospective analysis of Movement Disorder Patient Referrals for Functional Neurosurgery in the Neurosciences Department of Mater Dei Hospital
Objective: Malta has a population of just under 450 000. The estimated number of patients likely to benefit from functional neurosurgery including Deep Brain Stimulation…Anodic stimulation reduces corticospinal tract engagement in STN-DBS for Parkinson’s disease: a case report.
Objective: To seek how novel programming options modify the therapeutic window in a case of off-targeting DBS. Background: In Parkinson’s disease deep brain stimulation (DBS)…Deep Brain Stimulation of Anterior Globus Pallidus internus Reduces Impulsivity in Parkinson’s Disease
Objective: To evaluate whether selective deep brain stimulation (DBS) stimulation of anterior region of globus pallidus internus (GPi) affects impulsivity in Parkinson’s Disease patients Background:…
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