Are transventricular approaches associated with increased haemorrhage in functional stereotactic neurosurgery? A comparative study on 550 patients
Objective: We investigate the comparative occurence of haemorrhage with or without transventricular apporaches in a large series of patients operated over two decades. Background: Accurate…Surgery‐related 30-day morbidity of deep brain stimulation in a large cohort of 600 patients
Objective: In this retrospective study we analyzed the surgery‐ and hardware‐related morbidity of deep brain stimulation within 30 days after surgery. Background: 600 functional stereotactic…The SUNRISE-PD Study, a clinical trial of AXO-LENTI-PD: a CNS-directed gene therapy for the treatment of Parkinson’s Disease
Objective: This presentation will provide an overview of the design and key objectives of the SUNRISE-PD study. Background: Parkinson’s disease (PD) is caused in part,…Pediatric Deep Brain Stimulation in Secondary Dystonia using Stereotactic Depth Electrode Targeting
Objective: The primary objective of our pediatric clinical research is to improve outcomes after deep brain stimulation for pediatric patients with secondary dystonia. We apply…Efficacy of Stereotactic lesioning in Multi-etiological tremor
Objective: Analyse our experience with Stereotactic lesioning for multi-etiological tremor. Background: Lesioning in tremor had been one of the most widely used procedures before the…Translation of a subject-specific stereotaxic platform to a large animal deep brain stimulation research models
Objective: To evaluate the feasibility and accuracy of applying the commercially-available, FHC STarFix platform system for direct targeting of deep brain stimulation electrodes in a…A Pilot Study of Gamma Knife Radiosurgery Targeting the Subthalamic Nucleus in Elderly and Infirmed Parkinson’s Disease Patients Not Amenable to Deep Brain Stimulation
Objective: To evaluate the safety and efficacy of unilateral subthalamic nucleus (STN) gamma knife surgery (GKS) in patients with Parkinson’s disease (PD) not amenable to…Stereotactic Lesioning of Nucleus Accumbens for Treatment of Aggression in Mental Retardation
Objective: To present and discuss a case of stereotactic ablation of bilateral nucleus accumbens (NAc) in a mentally retarded patient to alleviate symptoms of severe aggression.…Effect of Post-Operative Symptomatic Lead Edema Associated with Subthalamic Deep Brain Stimulation On Clinical Outcomes
Objective: To assess whether development of post-operative symptomatic edema around deep brain stimulation (DBS) leads impacts clinical outcomes. Background: Post-operative symptomatic delayed edema around the…Controlled neural organoids grafting promotes functional recovery in experimental parkinsonism
Objective: We propose that the striatal transplantation of 3D-neural organoids of controlled cell size and cell content, named "Controlled Neural Organoids" (CNOs), could circumvent the…
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